Category: immune
SEC23A Is an Independent Prognostic Biomarker in Bladder Cancer Correlated With MAPK Signaling
Clinical data mining and bioinformatics analysis can be employed effectively to elucidate the function and underlying mechanisms of the gene of interest. Here, we have proposed a framework for the identification and validation of independent biomarkers in human cancer and for mechanistic profiling using gene sets enrichment analysis and pathway analysis. This is followed by…
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Antihypertensive drug treatment and susceptibility to SARS-CoV-2 infection in human PSC-derived cardiomyocytes and primary endothelial cells
The pathogenicity of extreme acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been attributed to its skill to enter by means of the membrane-bound angiotensin-converting enzyme 2 (ACE2) receptor. Subsequently, it has been closely speculated that angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) remedy could modulate SARS-CoV-2 an infection. On this examine, publicity of human…
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Chimeric antigen receptor T cells
Are chimeric antigen receptor T cells (CAR-T cells) the longer term in immunotherapy for autoimmune ailments? Goal: CAR-T cell remedy has revolutionized the remedy of oncological ailments, and potential makes use of in autoimmune ailments have just lately been described. The evaluation goals to combine the obtainable knowledge on remedy with CAR-T cells, emphasizing autoimmune ailments, to find out…
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mPEG-Silane
The silane functionality in methoxy-PEG-silane allows the modification of a variety of surfaces (eg, glass, metals, particles) by PEGylation of such surfaces in a one-step process. These methoxy-PEGs are from our special PEG series, premium functional PEGs useful in various biomedical and biotechnological applications. Mole Weight: average of Mn 5,000 Polymer architecture shape: linear functionality:…
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Mycoplasma-Off Surface, 1L
Mycoplasma Off is used for cleaning and disinfecting all types of laboratory surfaces and devices, including safety cabinets, incubators, workbenches, sample storage boxes, and liquid nitrogen containers. Quickly effective against mycoplasma contamination, Mycoplasma Off ™ has broad antimicrobial activity against several other contaminants. Profits Convenient and Fast Mycoplasma Off ™ is a ready-to-use solution supplied…
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B-Galalactosidase Recombinant Aden
Background Recombinant adenoviruses have enormous potential in both research and therapeutic applications. There are numerous advantages in using adenovirus to introduce genetic material into host cells. The range of permissive host cells is very wide. The virus has been used to infect many types of mammalian cells (both replicative and non-replicative) for high expression of…
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Allium sativum Lectin (ASA)
Resume The immunomodulatory proteins present in garlic have recently been shown to be identical to the garlic lectins ASA I and ASA II [Clement F, Pramod SN, Venkatesh YP. In t. Immunopharmacol. 2010; 10: 316-324]. In this study, the stability of garlic lectins has been examined as a function of pH, temperature, and denaturants in…
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Hippeastrum hybrid Lectin (HHL)
Product name Hybrid Hippeastrum Lectin Full Product Name Hybrid Hippeastrum Lectin (HHL, Lectin Amaryllis, AL) (Biotin) Purity / Purification Degree in Molecular Biology Shape / Format Supplied as a powder in 10 mM HEPES, pH 7.5, 0.15 M sodium chloride, 0.08% sodium azide. Reconstitute with 1 ml of dH2O. Labeled with biotin. Preparation and storage…
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A framework for highly multiplexed dextramer mapping
A framework for extremely multiplexed dextramer mapping and prediction of T cell receptor sequences to antigen specificity T cell receptor (TCR) antigen-specific recognition is important for the adaptive immune system. Nonetheless, constructing a TCR-antigen interplay map has been difficult because of the staggering range of TCRs and antigens. Accordingly, extremely multiplexed dextramer-TCR binding assays have been lately developed, however…
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Why pets are so healthy for us The benefits of having a pet
Now that we are often at home because of the corona, more and more people are taking a dog or a cat; against boredom and to dispel loneliness. Does having a pet actually make you happier? Marie-José Enders-Slegers, professor by special appointment of anthrozoology, explains. The pets have not been dragged on since the start of…
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