medmk

Chimeric antigen receptor T cells

Are chimeric antigen receptor T cells (CAR-T cells) the longer term in immunotherapy for autoimmune ailments?

Goal: CAR-T cell remedy has revolutionized the remedy of oncological ailments, and potential makes use of in autoimmune ailments have just lately been described. The evaluation goals to combine the obtainable knowledge on remedy with CAR-T cells, emphasizing autoimmune ailments, to find out therapeutic advances and their potential future medical applicability in autoimmunity.

Supplies and strategies: A search was carried out in PubMed with the key phrases “Chimeric Antigen Receptor” and “CART cell”. The paperwork of curiosity had been chosen, and a crucial evaluation of the data was carried out.

Outcomes: Within the remedy of autoimmune ailments, in preclinical fashions, three completely different mobile methods have been used, which embrace Chimeric antigen receptor T cells, Chimeric autoantibody receptor T cells, and Chimeric antigen receptor in regulatory T lymphocytes. All three kinds of remedy have been efficient. The potential opposed results inside them, cytokine launch syndrome, mobile toxicity and neurotoxicity should all the time be saved in thoughts.

Conclusions: Though info in people will not be but obtainable, preclinical fashions of CAR-T cells within the remedy of autoimmune ailments present promising outcomes, in order that sooner or later, they might change into a helpful and efficient remedy within the remedy of those pathologies.

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EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV709564 1.0 ug DNA
EUR 379.2

EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV709565 1.0 ug DNA
EUR 448.8

EBAG9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV709566 1.0 ug DNA
EUR 448.8

EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV694976 1.0 ug DNA
EUR 616.8

EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV694977 1.0 ug DNA
EUR 686.4

EBAG9 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV694978 1.0 ug DNA
EUR 686.4

EBAG9 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)

LV709567 1.0 ug DNA
EUR 379.2

EBAG9 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

LV709568 1.0 ug DNA
EUR 379.2

EBAG9 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

LV694979 1.0 ug DNA
EUR 616.8

EBAG9 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

LV694980 1.0 ug DNA
EUR 616.8

IV Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730175 1.0 ug DNA Ask for price

HP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703719 1.0 ug DNA
EUR 540

C5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV704421 1.0 ug DNA
EUR 540

MS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV734267 1.0 ug DNA Ask for price

NA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV735845 1.0 ug DNA Ask for price

NM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV736283 1.0 ug DNA Ask for price

S7 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747677 1.0 ug DNA Ask for price

P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV739457 1.0 ug DNA Ask for price

CS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV709011 1.0 ug DNA
EUR 379.2

XM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756071 1.0 ug DNA Ask for price

XS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756089 1.0 ug DNA Ask for price

NP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV814299 1.0 ug DNA
EUR 540

DM1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723179 1.0 ug DNA Ask for price

DWS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723515 1.0 ug DNA Ask for price

EBM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723683 1.0 ug DNA Ask for price

EGI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723929 1.0 ug DNA Ask for price

F7R Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724757 1.0 ug DNA Ask for price

FND Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV725471 1.0 ug DNA Ask for price

UBB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV716529 1.0 ug DNA
EUR 379.2

WAC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV716727 1.0 ug DNA
EUR 379.2

AFA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV718313 1.0 ug DNA Ask for price

AIC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV718391 1.0 ug DNA Ask for price

AOM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV718865 1.0 ug DNA Ask for price

ATD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV719171 1.0 ug DNA Ask for price

GRN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710661 1.0 ug DNA
EUR 379.2

HGF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710829 1.0 ug DNA
EUR 379.2

HGF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710835 1.0 ug DNA
EUR 379.2

HYI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV711141 1.0 ug DNA
EUR 379.2

JTB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV711555 1.0 ug DNA
EUR 379.2

LBH Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV711897 1.0 ug DNA
EUR 379.2

LTF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712071 1.0 ug DNA
EUR 379.2

LUM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712083 1.0 ug DNA
EUR 379.2

LXN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712089 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712167 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712173 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712179 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712185 1.0 ug DNA
EUR 379.2

MPI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712365 1.0 ug DNA
EUR 379.2

NF2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712731 1.0 ug DNA
EUR 379.2

NMI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712773 1.0 ug DNA
EUR 379.2

OAT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712983 1.0 ug DNA
EUR 379.2

OS9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV713019 1.0 ug DNA
EUR 379.2

JBS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730193 1.0 ug DNA Ask for price

JPD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730199 1.0 ug DNA Ask for price

KFM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730349 1.0 ug DNA Ask for price

KMS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730469 1.0 ug DNA Ask for price

KSS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730745 1.0 ug DNA Ask for price

KWE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730751 1.0 ug DNA Ask for price

LCO Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730883 1.0 ug DNA Ask for price

GTS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV727145 1.0 ug DNA Ask for price

HMI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV728375 1.0 ug DNA Ask for price

HPT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV728723 1.0 ug DNA Ask for price

HTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV728969 1.0 ug DNA Ask for price

CHR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721169 1.0 ug DNA Ask for price

CMM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721403 1.0 ug DNA Ask for price

CNC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721451 1.0 ug DNA Ask for price

COP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721595 1.0 ug DNA Ask for price

CRG Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721781 1.0 ug DNA Ask for price

CRS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721793 1.0 ug DNA Ask for price

CSE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721835 1.0 ug DNA Ask for price

CTD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721919 1.0 ug DNA Ask for price

DCE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV722333 1.0 ug DNA Ask for price

DDU Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV722357 1.0 ug DNA Ask for price

RGR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV714303 1.0 ug DNA
EUR 379.2

Sp2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715317 1.0 ug DNA
EUR 379.2

Sp2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715323 1.0 ug DNA
EUR 379.2

Syk Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715605 1.0 ug DNA
EUR 379.2

TK1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715875 1.0 ug DNA
EUR 379.2

TTK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV716385 1.0 ug DNA
EUR 379.2

GCY Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV726557 1.0 ug DNA Ask for price

PIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV713469 1.0 ug DNA
EUR 379.2

PTS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV713985 1.0 ug DNA
EUR 379.2

CCT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV720665 1.0 ug DNA Ask for price

CCV Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV720719 1.0 ug DNA Ask for price

CRP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703479 1.0 ug DNA
EUR 540

NPL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703695 1.0 ug DNA
EUR 540

FGA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV704103 1.0 ug DNA
EUR 540

NNT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV704253 1.0 ug DNA
EUR 379.2

MSD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV734285 1.0 ug DNA Ask for price

NSX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV736493 1.0 ug DNA Ask for price

NT3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV736499 1.0 ug DNA Ask for price

OAP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV736655 1.0 ug DNA Ask for price

OED Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV736703 1.0 ug DNA Ask for price

PIH Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV740315 1.0 ug DNA Ask for price

PRD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV741569 1.0 ug DNA Ask for price

PRS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV741749 1.0 ug DNA Ask for price

SDU Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV748127 1.0 ug DNA Ask for price

SEA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV748133 1.0 ug DNA Ask for price

ST2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV749651 1.0 ug DNA
EUR 686.4

ST3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV749657 1.0 ug DNA Ask for price

ST4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV749669 1.0 ug DNA Ask for price

ST8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV749687 1.0 ug DNA Ask for price

RP6 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747185 1.0 ug DNA Ask for price

RSS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747629 1.0 ug DNA Ask for price

S11 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747683 1.0 ug DNA Ask for price

S12 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747689 1.0 ug DNA Ask for price

PDR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV739871 1.0 ug DNA Ask for price

MAA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732365 1.0 ug DNA Ask for price

MCO Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732641 1.0 ug DNA Ask for price

MEB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732671 1.0 ug DNA Ask for price

mF4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732743 1.0 ug DNA Ask for price

MLS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV733631 1.0 ug DNA Ask for price

MOK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV733685 1.0 ug DNA Ask for price

MPE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV733739 1.0 ug DNA Ask for price

HGF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV701979 1.0 ug DNA
EUR 540

CA8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708255 1.0 ug DNA
EUR 379.2

CA8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708261 1.0 ug DNA
EUR 379.2

CBS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708339 1.0 ug DNA
EUR 379.2

CBS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708345 1.0 ug DNA
EUR 379.2

CGA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708669 1.0 ug DNA
EUR 379.2

CKB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708753 1.0 ug DNA
EUR 379.2

CRK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708987 1.0 ug DNA
EUR 379.2

CRP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708993 1.0 ug DNA
EUR 379.2

CRP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708999 1.0 ug DNA
EUR 379.2

DTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV709467 1.0 ug DNA
EUR 379.2

EVL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV709839 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710247 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710253 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710259 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710265 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710271 1.0 ug DNA
EUR 379.2

FUZ Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710289 1.0 ug DNA
EUR 379.2

GIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710403 1.0 ug DNA
EUR 379.2

C8A Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV702501 1.0 ug DNA
EUR 540

SLN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV702969 1.0 ug DNA
EUR 540

LY9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703815 1.0 ug DNA
EUR 540

LY9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705291 1.0 ug DNA
EUR 540

DUT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705459 1.0 ug DNA
EUR 540

NPL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705585 1.0 ug DNA
EUR 540

BMF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705639 1.0 ug DNA
EUR 540

FTO Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705999 1.0 ug DNA
EUR 540

MIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV706503 1.0 ug DNA
EUR 540

AEN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707157 1.0 ug DNA
EUR 379.2

AEN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707163 1.0 ug DNA
EUR 379.2

AGK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707187 1.0 ug DNA
EUR 379.2

ALB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707271 1.0 ug DNA
EUR 379.2

ANG Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707325 1.0 ug DNA
EUR 379.2

ATM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707655 1.0 ug DNA
EUR 379.2

BID Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707847 1.0 ug DNA
EUR 379.2

BMF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707871 1.0 ug DNA
EUR 379.2

BMF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707877 1.0 ug DNA
EUR 379.2

FTX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV761753 1.0 ug DNA
EUR 1104

CPP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV759281 1.0 ug DNA
EUR 2148

CPQ Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV759287 1.0 ug DNA
EUR 686.4

TYS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV754913 1.0 ug DNA Ask for price

VCF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755573 1.0 ug DNA Ask for price

VDI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755609 1.0 ug DNA Ask for price

WSN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755987 1.0 ug DNA Ask for price

WT2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755993 1.0 ug DNA Ask for price

WTS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755999 1.0 ug DNA Ask for price

WWS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756017 1.0 ug DNA Ask for price

XCE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756041 1.0 ug DNA Ask for price

XGR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756047 1.0 ug DNA Ask for price

XIC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756059 1.0 ug DNA Ask for price

TDD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV750293 1.0 ug DNA Ask for price

Ovalbumin Antigen-Particular Activation of Human T Cell Receptor Intently Resembles Soluble Antibody Stimulation as Revealed by BOOST Phosphotyrosine Proteomics

Activation of the T cell receptor (TCR) results in a community of early signaling predominantly orchestrated by tyrosine phosphorylation in T cells. The TCR is often activated utilizing soluble anti-TCR antibodies, however this strategy will not be antigen-specific. Alternatively, activating the TCR utilizing particular antigens of a variety of binding affinities within the type of a peptide-major histocompatibility complicated (pMHC) is presumed to be extra physiological. Nonetheless, because of the lack of wide-scale phosphotyrosine (pTyr) proteomic research straight evaluating anti-TCR antibodies and pMHC, a complete definition of those activated states stays enigmatic.

Elucidation of the tyrosine phosphoproteome utilizing quantitative pTyr proteomics allows a greater understanding of the distinctive options of those activating brokers and the position of ligand binding affinity on signaling. Right here, we apply the just lately established Broad-spectrum Optimization Of Selective Triggering (BOOST) to look at perturbations in tyrosine phosphorylation of human TCR triggered by anti-TCR antibodies and pMHC. Our knowledge reveal that high-affinity ovalbumin (OVA) pMHC activation of the human TCR triggers a largely related, albeit probably stronger, pTyr-mediated signaling regulatory axis in comparison with the anti-TCR antibody. The signaling output ensuing from OVA pMHC variants correlates properly with their weaker affinities, enabling affinity-tunable management of signaling power. Collectively, we offer a framework for making use of BOOST to match pTyr-mediated signaling pathways of human T cells activated in an antigen-independent and antigen-specific method.

Bilateral anterior cerebral artery occlusion following CD19- and BCMA-targeted chimeric antigen receptor T-cell remedy for a myeloma affected person

Chimeric antigen receptor T (CAR-T)-cell remedy is a promising remedy for relapsed/refractory a number of myeloma (RRMM). In our earlier report, CD19- and BCMA-targeted CAR-T co-administration was related to a excessive response fee. Though cytokine launch syndrome (CRS) and neurotoxicity are frequent problems following CAR-T remedy, cerebral infarction isn’t reported as a CAR-T-related complication. We reported a 73-year-old feminine MM affected person who acquired CD19- and BCMA-targeted CAR-T for refractory illness.

Her illness responded to CAR-T remedy, however she developed neurological signs following CRS. Cranial CT and MRI demonstrated a number of cerebral infarctions and bilateral anterior cerebral artery (ACA) occlusion. We recommend that cerebral infarction apart from CAR-T-related neurotoxicity is the underlying explanation for irregular neuropsychological signs, and diagnostic imaging exams must be actively carried out to exclude ischemic cerebrovascular occasions.

The Intracellular Area of CD40 is a Potent Costimulatory Aspect in Chimeric Antigen Receptors

The costimulatory domains integrated into second-generation and third-generation chimeric antigen receptors (CARs) strongly affect CAR-T-cell operate. Right here, we explored second-generation and third-generation CARs harboring the signaling area of the CD40 receptor as a brand new costimulatory component compared with related CARs carrying the 4-1BB area. In CARs of each generations, CD40 was stronger than 4-1BB in triggering the NF-κB signaling pathway.

In human T cells from 2 donors, CD40 was akin to 4-1BB in upregulating costimulatory and activation markers, inducing proinflammatory cytokine secretion and mediating goal cell killing. Apparently, variations within the response sample of T cells from the two donors with respect to CD40 and 4-1BB had been evident. We conclude that in human T cells, the CD40 signaling area is a potent costimulatory component in each second-generation and third-generation CARs.

A Systematic Evaluation of the Function of Chimeric Antigen Receptor T (CAR-T) Cell Remedy within the Remedy of Strong Tumors

Chimeric antigen receptor T (CAR-T) cell remedy makes use of sufferers’ personal T lymphocytes which might be engineered to assault most cancers cells. It’s Meals and Drug Administration (FDA)-approved in numerous hematological malignancies and at the moment being evaluated in stable cancers in early part research. We did a scientific evaluation consisting of 15 potential medical trials (n=159) evaluating CAR-T cells in stable cancers. Early part trials confirmed promising response charges in ovarian epithelial most cancers (100%), human epidermal development issue receptor 2 (HER2)-positive sarcoma (67%), epidermal development issue receptor (EGFR)-positive biliary tract most cancers (65%), superior gastric/pancreatic most cancers (82%), hepatocellular carcinoma (67%), and colorectal most cancers (70%).

The median total response throughout all malignancies was 62% (vary 17%-100%). Median progression-free survival and total survival weren’t reached in most trials. Cytokine launch syndrome was seen in just one affected person with cholangiocarcinoma who acquired EGFR-specific CAR-T cell remedy. Though survival knowledge continues to be not mature, CAR-T cell remedy in stable malignancies did present encouraging response charges and was well-tolerated.

Variations in lymphoma sufferers between chimeric antigen receptor T-cell remedy trials and the overall inhabitants

Chimeric antigen receptor (CAR)-T cell therapies seem to be promising remedies for non-Hodgkin’s and B-cell lymphoma. Nonetheless, a number of CAR-T therapies authorised by the US Meals and Drug Administration have solely been examined for efficacy in comparatively few single-arm medical trials with small pattern sizes. We sought to look at the variations between sufferers in these trials and the overall inhabitants of sufferers with non-Hodgkin’s and B-cell lymphoma. 5 hundred and twenty-two sufferers from 15 CAR-T trials present in a scientific evaluation and 417,492 sufferers from the Surveillance, Epidemiology, and Finish Outcomes (SEER) Program database had been in contrast.

CAR-T examine members seemed to be youthful (46.7% beneath 70 years outdated vs. 42.2%), extra male (68.0% vs. 55.7%), and adopted for a shorter time period in comparison with sufferers within the SEER inhabitants (imply [M] 45.6 months, 95% confidence interval [CI] 17.7 to 63.three months follow-up vs. M 57.1 months, 95% CI 57.Zero to 57.three months survival). CAR-T examine members could differ considerably from the overall inhabitants of sufferers with non-Hodgkin’s and B-cell lymphoma. Effectiveness of CAR-T therapies within the basic inhabitants of lymphoma sufferers could differ from effectiveness demonstrated in trials. Newly created CAR-T affected person registries are important to establishing population-level effectiveness of the therapies.

ITGB1, 21-465aa, Human, His tag, E Coli (Denatured)

MBS205044-05mg 0.5mg
EUR 765

ITGB1, 21-465aa, Human, His tag, E Coli (Denatured)

MBS205044-5x05mg 5x0.5mg
EUR 3195

SIL1, 32-461aa, Human, His tag, E Coli

MBS204276-001mg 0.01mg
EUR 230

SIL1, 32-461aa, Human, His tag, E Coli

MBS204276-002mg 0.02mg
EUR 295

SIL1, 32-461aa, Human, His tag, E Coli

MBS204276-005mg 0.05mg
EUR 350

SIL1, 32-461aa, Human, His tag, E Coli

MBS204276-01mg 0.1mg
EUR 505

SIL1, 32-461aa, Human, His tag, E Coli

MBS204276-025mg 0.25mg
EUR 790

ODC1, 1-461aa, Human, His tag, E Coli

MBS204706-001mg 0.01mg
EUR 230

ODC1, 1-461aa, Human, His tag, E Coli

MBS204706-005mg 0.05mg
EUR 405

ODC1, 1-461aa, Human, His tag, E Coli

MBS204706-025mg 0.25mg
EUR 985

ODC1, 1-461aa, Human, His tag, E Coli

MBS204706-5x025mg 5x0.25mg
EUR 4180

ITGB1, 1-728aa, Human, His-tag, Baculovirus

MBS206555-001mg 0.01mg
EUR 215

ITGB1, 1-728aa, Human, His-tag, Baculovirus

MBS206555-002mg 0.02mg
EUR 255

ITGB1, 1-728aa, Human, His-tag, Baculovirus

MBS206555-005mg 0.05mg
EUR 340

ITGB1, 1-728aa, Human, His-tag, Baculovirus

MBS206555-01mg 0.1mg
EUR 470

ITGB1, 1-728aa, Human, His-tag, Baculovirus

MBS206555-025mg 0.25mg
EUR 765

GWB-ATG485-20UG - FSTL1, 21-308aa, Human, His tag, E.coli

GWB-ATG485-20UG 20ug
EUR 330

GWB-ATG485-100UG - FSTL1, 21-308aa, Human, His tag, E.coli

GWB-ATG485-100UG 100ug
EUR 990

ITGB1BP3, 1-230aa, Human, His tag, E Coli

MBS204773-0004mg 0.004mg
EUR 215

ITGB1BP3, 1-230aa, Human, His tag, E Coli

MBS204773-002mg 0.02mg
EUR 340

ITGB1BP3, 1-230aa, Human, His tag, E Coli

MBS204773-01mg 0.1mg
EUR 765

ITGB1BP3, 1-230aa, Human, His tag, E Coli

MBS204773-5x01mg 5x0.1mg
EUR 3195

Recombinant Human ITGB1 Protein, His, E.coli-10ug

QP12462-HIS-10ug 10ug
EUR 241.2

Recombinant Human ITGB1 Protein, His, E.coli-20ug

QP12462-HIS-20ug 20ug
EUR 241.2

Recombinant Human ITGB1 Protein, His, E.coli-2ug

QP12462-HIS-2ug 2ug
EUR 186

Recombinant Human ITGB1 Protein, His, E.coli-5ug

QP12462-HIS-5ug 5ug
EUR 186

Recombinant Human ITGB1 Protein, His, E.coli-1mg

QP12462-HIS-EC-1mg 1mg
EUR 3308.4

ITGB3BP, 1-216aa, Human His tag, E Coli (Denatured)

MBS205043-0004mg 0.004mg
EUR 215

ITGB3BP, 1-216aa, Human His tag, E Coli (Denatured)

MBS205043-002mg 0.02mg
EUR 340

ITGB3BP, 1-216aa, Human His tag, E Coli (Denatured)

MBS205043-01mg 0.1mg
EUR 765

ITGB3BP, 1-216aa, Human His tag, E Coli (Denatured)

MBS205043-5x01mg 5x0.1mg
EUR 3195

Human ITGA6 & ITGB1 Protein, His Tag

E40KMPH5766 20ug
EUR 495

B2M, 21-119aa, Human, His tag, E Coli

MBS203578-001mg 0.01mg
EUR 340

B2M, 21-119aa, Human, His tag, E Coli

MBS203578-005mg 0.05mg
EUR 765

B2M, 21-119aa, Human, His tag, E Coli

MBS203578-5x005mg 5x0.05mg
EUR 3195

C8G, 21-202aa, Human, His tag, E Coli

MBS204109-002mg 0.02mg
EUR 215

C8G, 21-202aa, Human, His tag, E Coli

MBS204109-01mg 0.1mg
EUR 340

C8G, 21-202aa, Human, His tag, E Coli

MBS204109-05mg 0.5mg
EUR 765

C8G, 21-202aa, Human, His tag, E Coli

MBS204109-5x05mg 5x0.5mg
EUR 3195

CHGB, 21-677aa, Human, His tag, E Coli

MBS203715-001mg 0.01mg
EUR 230

CHGB, 21-677aa, Human, His tag, E Coli

MBS203715-005mg 0.05mg
EUR 405

CHGB, 21-677aa, Human, His tag, E Coli

MBS203715-025mg 0.25mg
EUR 985

CHGB, 21-677aa, Human, His tag, E Coli

MBS203715-5x025mg 5x0.25mg
EUR 4180

LCN2, 21-198aa, Human, His tag, E Coli

MBS203944-002mg 0.02mg
EUR 230

LCN2, 21-198aa, Human, His tag, E Coli

MBS203944-01mg 0.1mg
EUR 405

LCN2, 21-198aa, Human, His tag, E Coli

MBS203944-05mg 0.5mg
EUR 985

LCN2, 21-198aa, Human, His tag, E Coli

MBS203944-5x05mg 5x0.5mg
EUR 4180

MRM1, 21-353aa, Human, His tag, E Coli

MBS205099-001mg 0.01mg
EUR 230

MRM1, 21-353aa, Human, His tag, E Coli

MBS205099-005mg 0.05mg
EUR 405

MRM1, 21-353aa, Human, His tag, E Coli

MBS205099-025mg 0.25mg
EUR 985

MRM1, 21-353aa, Human, His tag, E Coli

MBS205099-5x025mg 5x0.25mg
EUR 4180

LY6D, 21-98aa, Human, His tag, E Coli

MBS205508-002mg 0.02mg
EUR 215

LY6D, 21-98aa, Human, His tag, E Coli

MBS205508-01mg 0.1mg
EUR 340

LY6D, 21-98aa, Human, His tag, E Coli

MBS205508-05mg 0.5mg
EUR 765

LY6D, 21-98aa, Human, His tag, E Coli

MBS205508-5x05mg 5x0.5mg
EUR 3195

CD40, 21-193aa, Human, His tag, E Coli

MBS205519-001mg 0.01mg
EUR 215

CD40, 21-193aa, Human, His tag, E Coli

MBS205519-005mg 0.05mg
EUR 340

CD40, 21-193aa, Human, His tag, E Coli

MBS205519-025mg 0.25mg
EUR 765

CD40, 21-193aa, Human, His tag, E Coli

MBS205519-5x025mg 5x0.25mg
EUR 3195

CST1, 21-141aa, Human, His tag, E Coli

MBS204735-002mg 0.02mg
EUR 215

CST1, 21-141aa, Human, His tag, E Coli

MBS204735-01mg 0.1mg
EUR 340

CST1, 21-141aa, Human, His tag, E Coli

MBS204735-05mg 0.5mg
EUR 765

CST1, 21-141aa, Human, His tag, E Coli

MBS204735-5x05mg 5x0.5mg
EUR 3195

RCN3, 21-328aa, Human, His tag, E Coli

MBS204418-002mg 0.02mg
EUR 215

RCN3, 21-328aa, Human, His tag, E Coli

MBS204418-01mg 0.1mg
EUR 340

RCN3, 21-328aa, Human, His tag, E Coli

MBS204418-05mg 0.5mg
EUR 765

RCN3, 21-328aa, Human, His tag, E Coli

MBS204418-5x05mg 5x0.5mg
EUR 3195

CST4, 21-141aa, Human, His tag, E Coli

MBS204592-002mg 0.02mg
EUR 215

CST4, 21-141aa, Human, His tag, E Coli

MBS204592-01mg 0.1mg
EUR 340

CST4, 21-141aa, Human, His tag, E Coli

MBS204592-05mg 0.5mg
EUR 765

CST4, 21-141aa, Human, His tag, E Coli

MBS204592-5x05mg 5x0.5mg
EUR 3195

AGRP, 21-132aa, Human, His tag, E Coli

MBS206129-001mg 0.01mg
EUR 205

AGRP, 21-132aa, Human, His tag, E Coli

MBS206129-002mg 0.02mg
EUR 250

AGRP, 21-132aa, Human, His tag, E Coli

MBS206129-005mg 0.05mg
EUR 285

AGRP, 21-132aa, Human, His tag, E Coli

MBS206129-01mg 0.1mg
EUR 380

AGRP, 21-132aa, Human, His tag, E Coli

MBS206129-025mg 0.25mg
EUR 580

MuCL1, 21-90aa, Human, His tag, E Coli

MBS205906-0004mg 0.004mg
EUR 215

MuCL1, 21-90aa, Human, His tag, E Coli

MBS205906-002mg 0.02mg
EUR 340

MuCL1, 21-90aa, Human, His tag, E Coli

MBS205906-01mg 0.1mg
EUR 765

MuCL1, 21-90aa, Human, His tag, E Coli

MBS205906-5x01mg 5x0.1mg
EUR 3195

PDIA4, 21-645aa, Human, His tag, E Coli

MBS203661-001mg 0.01mg
EUR 230

PDIA4, 21-645aa, Human, His tag, E Coli

MBS203661-005mg 0.05mg
EUR 405

PDIA4, 21-645aa, Human, His tag, E Coli

MBS203661-025mg 0.25mg
EUR 985

PDIA4, 21-645aa, Human, His tag, E Coli

MBS203661-5x025mg 5x0.25mg
EUR 4180

TREM1, 21-205aa, Human, His tag, E Coli

MBS204245-002mg 0.02mg
EUR 215

TREM1, 21-205aa, Human, His tag, E Coli

MBS204245-01mg 0.1mg
EUR 340

TREM1, 21-205aa, Human, His tag, E Coli

MBS204245-05mg 0.5mg
EUR 765

TREM1, 21-205aa, Human, His tag, E Coli

MBS204245-5x05mg 5x0.5mg
EUR 3195

MSRB3, 21-185aa, Human, His tag, E Coli

MBS203811-001mg 0.01mg
EUR 230

MSRB3, 21-185aa, Human, His tag, E Coli

MBS203811-005mg 0.05mg
EUR 405

MSRB3, 21-185aa, Human, His tag, E Coli

MBS203811-025mg 0.25mg
EUR 985

MSRB3, 21-185aa, Human, His tag, E Coli

MBS203811-5x025mg 5x0.25mg
EUR 4180

PSMB9, 21-219aa, Human, His tag, E Coli

MBS203848-001mg 0.01mg
EUR 215

PSMB9, 21-219aa, Human, His tag, E Coli

MBS203848-005mg 0.05mg
EUR 340

PSMB9, 21-219aa, Human, His tag, E Coli

MBS203848-025mg 0.25mg
EUR 765

PSMB9, 21-219aa, Human, His tag, E Coli

MBS203848-5x025mg 5x0.25mg
EUR 3195

MSRB2, 21-182aa, Human, His tag, E Coli

MBS203879-002mg 0.02mg
EUR 215

MSRB2, 21-182aa, Human, His tag, E Coli

MBS203879-01mg 0.1mg
EUR 340

MSRB2, 21-182aa, Human, His tag, E Coli

MBS203879-05mg 0.5mg
EUR 765

MSRB2, 21-182aa, Human, His tag, E Coli

MBS203879-5x05mg 5x0.5mg
EUR 3195

BOLA1, 21-137aa, Human, His tag, E Coli

MBS205376-002mg 0.02mg
EUR 215

BOLA1, 21-137aa, Human, His tag, E Coli

MBS205376-01mg 0.1mg
EUR 340

BOLA1, 21-137aa, Human, His tag, E Coli

MBS205376-05mg 0.5mg
EUR 765

BOLA1, 21-137aa, Human, His tag, E Coli

MBS205376-5x05mg 5x0.5mg
EUR 3195

FSTL1, 21-308aa, Human, His tag, E Coli

MBS204927-001mg 0.01mg
EUR 240

FSTL1, 21-308aa, Human, His tag, E Coli

MBS204927-002mg 0.02mg
EUR 320

FSTL1, 21-308aa, Human, His tag, E Coli

MBS204927-005mg 0.05mg
EUR 375

FSTL1, 21-308aa, Human, His tag, E Coli

MBS204927-01mg 0.1mg
EUR 550

FSTL1, 21-308aa, Human, His tag, E Coli

MBS204927-025mg 0.25mg
EUR 885

HS3ST1, 21-307aa, Human, His tag, E Coli

MBS205156-001mg 0.01mg
EUR 215

HS3ST1, 21-307aa, Human, His tag, E Coli

MBS205156-005mg 0.05mg
EUR 340

HS3ST1, 21-307aa, Human, His tag, E Coli

MBS205156-025mg 0.25mg
EUR 765

HS3ST1, 21-307aa, Human, His tag, E Coli

MBS205156-5x025mg 5x0.25mg
EUR 3195

Midkine, 21-143aa, Human, His tag, E Coli

MBS203354-002mg 0.02mg
EUR 215

Midkine, 21-143aa, Human, His tag, E Coli

MBS203354-01mg 0.1mg
EUR 340

Midkine, 21-143aa, Human, His tag, E Coli

MBS203354-05mg 0.5mg
EUR 765

Midkine, 21-143aa, Human, His tag, E Coli

MBS203354-5x05mg 5x0.5mg
EUR 3195

DEFB118, 21-123aa, Human, His tag, E Coli

MBS204950-002mg 0.02mg
EUR 215

DEFB118, 21-123aa, Human, His tag, E Coli

MBS204950-01mg 0.1mg
EUR 340

DEFB118, 21-123aa, Human, His tag, E Coli

MBS204950-05mg 0.5mg
EUR 765

DEFB118, 21-123aa, Human, His tag, E Coli

MBS204950-5x05mg 5x0.5mg
EUR 3195

Vaspin, 21- 414aa, Human, His tag, E Coli

MBS203100-002mg 0.02mg
EUR 275

Vaspin, 21- 414aa, Human, His tag, E Coli

MBS203100-01mg 0.1mg
EUR 550

Vaspin, 21- 414aa, Human, His tag, E Coli

MBS203100-05mg 0.5mg
EUR 1410

Vaspin, 21- 414aa, Human, His tag, E Coli

MBS203100-5x05mg 5x0.5mg
EUR 6110

Human Integrin b1 / ITGB1 / CD29, His Tag

E24PHA397 50 μg
EUR 332

Human ITGA2 & ITGB1 Heterodimer Protein, His Tag & hFc Tag

MBS189055-001mg 0.01mg
EUR 235

Human ITGA2 & ITGB1 Heterodimer Protein, His Tag & hFc Tag

MBS189055-005mg 0.05mg
EUR 435

Human ITGA2 & ITGB1 Heterodimer Protein, His Tag & hFc Tag

MBS189055-5x005mg 5x0.05mg
EUR 1655

AGR 2, 21-175aa, Human, His tag, E Coli

MBS203107-002mg 0.02mg
EUR 215

AGR 2, 21-175aa, Human, His tag, E Coli

MBS203107-01mg 0.1mg
EUR 340

AGR 2, 21-175aa, Human, His tag, E Coli

MBS203107-05mg 0.5mg
EUR 765

AGR 2, 21-175aa, Human, His tag, E Coli

MBS203107-5x05mg 5x0.5mg
EUR 3195

SAA,4, 21-130aa, Human, His tag, E Coli

MBS203993-001mg 0.01mg
EUR 240

SAA,4, 21-130aa, Human, His tag, E Coli

MBS203993-002mg 0.02mg
EUR 320

SAA,4, 21-130aa, Human, His tag, E Coli

MBS203993-005mg 0.05mg
EUR 375

SAA,4, 21-130aa, Human, His tag, E Coli

MBS203993-01mg 0.1mg
EUR 550

SAA,4, 21-130aa, Human, His tag, E Coli

MBS203993-025mg 0.25mg
EUR 885

Human ITGA8 & ITGB1 Protein, His & Flag Tag

E40KMPH5768 20ug
EUR 495

Recombinant Human ITGB1 protein, N - His tag

MBS157667-005mg 0.05mg
EUR 320

Recombinant Human ITGB1 protein, N - His tag

MBS157667-01mg 0.1mg
EUR 410

Recombinant Human ITGB1 protein, N - His tag

MBS157667-5x01mg 5x0.1mg
EUR 1520

GPX3 (u73C), 21-226aa, Human, His tag, E Coli

MBS204302-001mg 0.01mg
EUR 230

GPX3 (u73C), 21-226aa, Human, His tag, E Coli

MBS204302-005mg 0.05mg
EUR 405

GPX3 (u73C), 21-226aa, Human, His tag, E Coli

MBS204302-025mg 0.25mg
EUR 985

GPX3 (u73C), 21-226aa, Human, His tag, E Coli

MBS204302-5x025mg 5x0.25mg
EUR 4180

Recombinant Human CD29/ITGB1 Protein, His Tag

E40KMH184 20ug
EUR 495

CGB, 21-165aa, Human, His tag, E Coli (Denatured)

MBS205434-002mg 0.02mg
EUR 215

CGB, 21-165aa, Human, His tag, E Coli (Denatured)

MBS205434-01mg 0.1mg
EUR 340

CGB, 21-165aa, Human, His tag, E Coli (Denatured)

MBS205434-05mg 0.5mg
EUR 765

CGB, 21-165aa, Human, His tag, E Coli (Denatured)

MBS205434-5x05mg 5x0.5mg
EUR 3195

LIPG, 21-340aa, Human, His tag, E Coli (Denatured)

MBS205626-002mg 0.02mg
EUR 215

LIPG, 21-340aa, Human, His tag, E Coli (Denatured)

MBS205626-01mg 0.1mg
EUR 340

LIPG, 21-340aa, Human, His tag, E Coli (Denatured)

MBS205626-05mg 0.5mg
EUR 765

LIPG, 21-340aa, Human, His tag, E Coli (Denatured)

MBS205626-5x05mg 5x0.5mg
EUR 3195

ARSA, 21-509aa, Human, His tag, E Coli (Denatured)

MBS205081-002mg 0.02mg
EUR 215

ARSA, 21-509aa, Human, His tag, E Coli (Denatured)

MBS205081-01mg 0.1mg
EUR 340

ARSA, 21-509aa, Human, His tag, E Coli (Denatured)

MBS205081-05mg 0.5mg
EUR 765

ARSA, 21-509aa, Human, His tag, E Coli (Denatured)

MBS205081-5x05mg 5x0.5mg
EUR 3195

LY86, 21-162aa, Human, His tag, E Coli (Denatured)

MBS205105-002mg 0.02mg
EUR 215

LY86, 21-162aa, Human, His tag, E Coli (Denatured)

MBS205105-01mg 0.1mg
EUR 340

LY86, 21-162aa, Human, His tag, E Coli (Denatured)

MBS205105-05mg 0.5mg
EUR 765

LY86, 21-162aa, Human, His tag, E Coli (Denatured)

MBS205105-5x05mg 5x0.5mg
EUR 3195

JAM2, 21-238aa, Human, His tag, E Coli (Denatured)

MBS204951-002mg 0.02mg
EUR 215

JAM2, 21-238aa, Human, His tag, E Coli (Denatured)

MBS204951-01mg 0.1mg
EUR 340

JAM2, 21-238aa, Human, His tag, E Coli (Denatured)

MBS204951-05mg 0.5mg
EUR 765

JAM2, 21-238aa, Human, His tag, E Coli (Denatured)

MBS204951-5x05mg 5x0.5mg
EUR 3195

TSHB, 21-138aa, Human, His tag, E Coli (Denatured)

MBS204965-0004mg 0.004mg
EUR 215

TSHB, 21-138aa, Human, His tag, E Coli (Denatured)

MBS204965-002mg 0.02mg
EUR 340

TSHB, 21-138aa, Human, His tag, E Coli (Denatured)

MBS204965-01mg 0.1mg
EUR 765

TSHB, 21-138aa, Human, His tag, E Coli (Denatured)

MBS204965-5x01mg 5x0.1mg
EUR 3195

uGT8, 21-541aa, Human, His tag, E Coli (Denatured)

MBS205035-002mg 0.02mg
EUR 215

uGT8, 21-541aa, Human, His tag, E Coli (Denatured)

MBS205035-01mg 0.1mg
EUR 340

uGT8, 21-541aa, Human, His tag, E Coli (Denatured)

MBS205035-05mg 0.5mg
EUR 765

uGT8, 21-541aa, Human, His tag, E Coli (Denatured)

MBS205035-5x05mg 5x0.5mg
EUR 3195

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