Medical Mitogen-activated protein kinases (MAPK) Research

anti- Phospoho CDK, MAPK, GSK3, CLK, ERK1/2, JNK

Unravelling the selectivity of 6,7 dimethyl Quinoxaline analogues for kinase inhibition: An Insight towards the development of Alzheimer's therapeutics
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Unravelling the selectivity of 6,7 dimethyl Quinoxaline analogues for kinase inhibition: An Insight towards the development of Alzheimer’s therapeutics

Untangling probably the most selective kinase inhibitors by way of pharmacological intervention stays one of many difficult affairs thus far. Inaccordance to this drift, herein we describe the design and synthesis of a set of recent heterocyclic analogues consisting of 6,7 dimethyl Quinoxaline, appended to a connector, using Schiff base technique (Compounds I – IX ).
The compounds had been characterised by numerous spectroscopic strategies and the kinase inhibition assay had been carried out on few prime members of the CMGC household specifically the GSK3 b , DYRK1A and CLK1 receptors respectively, which were identified to be straight concerned in hyperphosphorylation of Tau.
Curiously the organic analysis outcomes revealed that Compounds IV & V , with bromo/chloro functionalities within the fragrant core had been advantaged of being extremely selective in the direction of the goal GSK3b over others.
To strengthen our evaluation, we adopted molecular modelling research, the place compounds IV /V had been redocked in the identical grid 4AFJ, as that of the reference ligand, 5-Aryl-4-Carboxamide-1,3-Oxazole. Surprisingly, our investigation underpined that for each the compounds IV/V, a major H-bonding existed between the designed molecules ( IV/V) and Val 135 residue within the receptor GSK3b, inline with the reference ligand. We attribute this interplay to instigate efficiency within the compounds.
Certainly the opposite non-covalent interplay, between the by-product’s fragrant nucleus and Arg 141/Thr 138 within the receptor GSK3b, might need been answerable for enhancing the selectivity within the targets. Total, we really feel that the current work depicts a logical demonstration in the direction of advantageous tuning the efficacy of the inhibitors by way of systematic adjustment of electron density at acceptable positions within the fragrant ring be it the primary quinoxaline or the opposite fragrant nucleus. Thus this pathway presents a handy technique for the event of environment friendly therapeutics for diversified neurodegenerative ailments like that of Alzheimer’s.

GSK3 as a Regulator of Cytoskeleton Structure: Penalties for Well being and Illness

Glycogen synthase kinase 3 (GSK3) was initially remoted as a vital protein in vitality metabolism. Nonetheless, subsequent research point out that GSK-Three is a multi-tasking kinase that hyperlinks quite a few signaling pathways in a cell and performs an important position within the regulation of many elements of mobile physiology.
As a regulator of actin and tubulin cytoskeleton, GSK3 influences processes of cell polarization, interplay with the extracellular matrix, and directional migration of cells and their organelles throughout the progress and growth of an animal organism. On this assessment, the roles of GSK3-cytoskeleton interactions in mind growth and pathology, migration of wholesome and most cancers cells, and in mobile trafficking of mitochondria shall be mentioned.
Unravelling the selectivity of 6,7 dimethyl Quinoxaline analogues for kinase inhibition: An Insight towards the development of Alzheimer's therapeutics

An Overview of the Security, Effectivity, and Sign Pathways of Stem Cell Remedy for Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune illness that impacts a number of organs and tissues. Mesenchymal stem cells (MSCs) are thought-about a great supply for autoimmune illness and hematological illness remedy. This assessment will summarize the efficacy, security, and mechanisms of MSC remedy for SLE.
MSC remedy can scale back anti-dsDNA, antinuclear antigen (ANA), proteinuria, and serum creatinine in SLE sufferers. In animal fashions of SLE, MSC remedy additionally signifies that it might scale back anti-dsDNA, ANA, proteinuria, and serum creatinine and ameliorate renal pathology.
There aren’t any severe hostile occasions, treatment-related mortality, or tumor-related occasions in SLE sufferers after stem cell therapy. MSCs can inhibit inflammatory components, equivalent to MCP-1 and HMGB-1, and inhibit inflammation-related signaling pathways, such because the NF-κB, JAK/STAT, and Akt/GSK3β signaling pathways, to alleviate the lesions in SLE.

Mitotic WNT signalling orchestrates neurogenesis within the growing neocortex

The position of WNT/β-catenin signalling in mouse neocortex growth stays ambiguous. Most research reveal that WNT/β-catenin regulates progenitor self-renewal however others counsel it could additionally promote differentiation. Right here we discover the position of WNT/STOP signalling, which stabilizes proteins throughout G2/M by inhibiting glycogen synthase kinase (GSK3)-mediated protein degradation.
We present that mice mutant for cyclin Y and cyclin Y-like 1 (Ccny/l1), key regulators of WNT/STOP signalling, show decreased neurogenesis within the growing neocortex. Particularly, basal progenitors, which exhibit delayed cell cycle development, had been drastically decreased. Ccny/l1-deficient apical progenitors present decreased uneven division attributable to a rise in apical-basal astral microtubules.
We establish the neurogenic transcription components Sox4 and Sox11 as direct GSK3 targets which are stabilized by WNT/STOP signalling in basal progenitors throughout mitosis and that promote neuron technology. Our work reveals that WNT/STOP signalling drives cortical neurogenesis and identifies mitosis as a vital part for neural progenitor destiny.

GSK3s: nodes of multilayer regulation of plant growth and stress responses

Glycogen synthase kinase 3 (GSK3) relations are extremely conserved serine/threonine protein kinases in eukaryotes. Not like animals, vegetation have developed with a number of homologs of GSK3s concerned in a various array of organic processes. Rising proof means that GSK3s act as signaling hubs for integrating notion and transduction of numerous indicators required for plant growth and responses to abiotic and biotic cues.
Right here we assessment current advances in understanding the molecular interactions between GSK3s and an increasing spectrum of their upstream regulators and downstream substrates in vegetation. We additional focus on how GSK3s act as key signaling nodes of multilayer regulation of plant growth and stress response by way of both being regulated on the post-translational degree or regulating their substrates by way of phosphorylation.

A GSK3-SRF Axis Mediates Angiotensin II Induced Endothelin Transcription in Vascular Endothelial Cells

Endothelin, encoded by ET1, is a vasoactive substance primarily synthesized in vascular endothelial cells (VECs). Elevation of endothelin ranges, attributable to transcriptional hyperactivation, has been noticed in a bunch of cardiovascular ailments. We now have beforehand proven that serum response issue (SRF) is a regulator of ET1 transcription in VECs.
Right here we report that angiotensin II (Ang II) induced ET1 transcription paralleled activation of glycogen synthase kinase 3 (GSK3) in cultured VECs. GSK3 knockdown or pharmaceutical inhibition attenuated Ang II induced endothelin expression.
Unravelling the selectivity of 6,7 dimethyl Quinoxaline analogues for kinase inhibition: An Insight towards the development of Alzheimer's therapeutics
Of curiosity, the impact of GSK3 on endothelin transcription relied on the conserved SRF motif inside the ET1 promoter. Additional evaluation revealed that GSK3 interacted with and phosphorylated SRF at serine 224. Phosphorylation of SRF by GSK3 didn’t affect its recruitment to the ET1 promoter.
As an alternative, GSK3-mediated SRF phosphorylation potentiated its interplay with MRTF-A, a key co-factor for SRF, which helped recruit the chromatin transforming protein BRG1 to the ET1 promoter leading to augmented histone H3 acetylation/H3K4 trimethylation.

GSK3b antibody
70R-11869 100 ug
EUR 501.6
Description: Rabbit polyclonal GSK3b antibody

GSK3B antibody
70R-15005 100 ul
EUR 470.4
Description: Rabbit polyclonal GSK3B antibody

GSK3B antibody
70R-17615 50 ul
EUR 522
Description: Rabbit polyclonal GSK3B antibody

GSK3B Antibody
36918-100ul 100ul
EUR 302.4

GSK3B Antibody
ABD6806 100 ug
EUR 525.6

GSK3B Antibody
ABD7231 100 ug
EUR 525.6

GSK3B Antibody
1-CSB-PA009963GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human, Mouse, Rat, Pig. This antibody is Unconjugated. Tested in the following application: ELISA, WB

GSK3B Antibody
1-CSB-PA009963LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF; Recommended dilution: WB:1:2000-1:10000, IF:1:50-1:500

GSK3B Antibody
1-CSB-PA009038
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/5000

GSK3B Antibody
1-CSB-PA080166
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC;WB:1:1000-2000.IHC:1:200-500

GSK3B Antibody
CSB-PA939628- each
EUR 402
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

GSK3B Antibody
CSB-PA939628-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

GSK3B Antibody
1-CSB-PA002848
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IP, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IP:2-5ug/mglysate.ELISA:1/20000

GSK3B Antibody
F51046-0.08ML 0.08 ml
EUR 140.25
Description: GSK3B is a constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. May also mediate the development of insulin resistance by regulating activation of transcription factors. [UniProt]

GSK3B Antibody
F51046-0.4ML 0.4 ml
EUR 322.15
Description: GSK3B is a constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. May also mediate the development of insulin resistance by regulating activation of transcription factors. [UniProt]

Gsk3b Antibody
F44221-0.08ML 0.08 ml
EUR 140.25
Description: Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. May phosphorylate MUC1 and decrease the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1 (By similarity).

Gsk3b Antibody
F44221-0.4ML 0.4 ml
EUR 322.15
Description: Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. May phosphorylate MUC1 and decrease the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1 (By similarity).

GSK3A / GSK3B Antibody
20-abx328487
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

GSK3A/GSK3B Antibody
1-CSB-PA002838
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3A/GSK3B. Recognizes GSK3A/GSK3B from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

GSK3B (pY216) Antibody
20-abx123289
  • EUR 594.00
  • EUR 844.80
  • EUR 260.40
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

GSK3B (pY216) Antibody
20-abx000312
  • EUR 594.00
  • EUR 844.80
  • EUR 260.40
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

GSK3B Antibody, HRP conjugated
1-CSB-PA009963LB01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

GSK3B Antibody, FITC conjugated
1-CSB-PA009963LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

GSK3B Antibody, Biotin conjugated
1-CSB-PA009963LD01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

GSK3B Conjugated Antibody
C38353 100ul
EUR 476.4

GSK3B Conjugated Antibody
C36918 100ul
EUR 476.4

GSK3B Polyclonal Antibody
A72446
  • EUR 302.50
  • EUR 423.50
  • 50 ul
  • 100 ul

GSK3B Polyclonal Antibody
A72447
  • EUR 302.50
  • EUR 423.50
  • 50 ul
  • 100 ul

GSK3B Polyclonal Antibody
A72448
  • EUR 302.50
  • EUR 423.50
  • 50 ul
  • 100 ul

GSK3B Polyclonal Antibody
A72450
  • EUR 377.30
  • EUR 577.50
  • 50 ul
  • 100 ul

GSK3B Polyclonal Antibody
A62706
  • EUR 684.66
  • EUR 117.70
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

GSK3 beta Antibody / GSK3B
F54007-0.1ML 0.1 ml
EUR 322.15
Description: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Requires primed phosphorylation of the majority of its substrates. In skeletal muscle, contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. May also mediate the development of insulin resistance by regulating activation of transcription factors. Regulates protein synthesis by controlling the activity of initiation factor 2B (EIF2BE/EIF2B5) in the same manner as glycogen synthase. In Wnt signaling, GSK3B forms a multimeric complex with APC, AXIN1 and CTNNB1/beta-catenin and phosphorylates the N-terminus of CTNNB1 leading to its degradation mediated by ubiquitin/proteasomes. [UniProt]

GSK3B (Ab-9) Antibody
CSB-PA120951- each
EUR 402
Description: A polyclonal antibody against GSK3B (Ab-9). Recognizes GSK3B (Ab-9) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

GSK3B (Ab-9) Antibody
CSB-PA120951-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against GSK3B (Ab-9). Recognizes GSK3B (Ab-9) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

GSK3B (pS21 / 29) Antibody
abx031864-400ul 400 ul
EUR 627.6

GSK3B (pS21 / 29) Antibody
abx031864-80l 80 µl
EUR 343.2

Monoclonal GSK3B Antibody, Clone: 3D6B4
AMM05223G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human GSK3B. The antibodies are raised in Mouse and are from clone 3D6B4. This antibody is applicable in WB and IHC, FC, E

Rabbit Anti-Human GSK3B (aa 214-218) Polyclonal Antibody
CPB-1178RH 100 ul
EUR 552

GSK3A / GSK3B (pY279 / 216) Antibody
abx333212-100ul 100 ul
EUR 560.4

GSK3A / GSK3B (pY279 / 216) Antibody
20-abx328488
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Polyclonal Mouse Gsk3b Antibody (N-term)
APR04027G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Mouse Gsk3b (N-term). This antibody is tested and proven to work in the following applications:

Polyclonal GSK3B / GSK3 Beta Antibody
AMM05221G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human GSK3B / GSK3 Beta . This antibody is tested and proven to work in the following applications:

GSK3A / GSK3B (Ab-279 / 216) Antibody
abx332166-100ul 100 ul
EUR 510

GSK3A/GSK3B (Ab-279/216) Antibody
CSB-PA255909- each
EUR 402
Description: A polyclonal antibody against GSK3A/GSK3B (Ab-279/216). Recognizes GSK3A/GSK3B (Ab-279/216) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

GSK3A/GSK3B (Ab-279/216) Antibody
CSB-PA255909-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against GSK3A/GSK3B (Ab-279/216). Recognizes GSK3A/GSK3B (Ab-279/216) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Antibody for Human GSK3b (pSer9)
SPC-1384D 0.1ml
EUR 424.8
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is unconjugated.

Antibody for Human GSK3b (pSer9)
SPC-1384D-A390 0.1ml
EUR 481.2
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 390.

Antibody for Human GSK3b (pSer9)
SPC-1384D-A488 0.1ml
EUR 480
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 488.

Antibody for Human GSK3b (pSer9)
SPC-1384D-A565 0.1ml
EUR 480
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 565.

Antibody for Human GSK3b (pSer9)
SPC-1384D-A594 0.1ml
EUR 480
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 594.

Antibody for Human GSK3b (pSer9)
SPC-1384D-A633 0.1ml
EUR 480
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 633.

Antibody for Human GSK3b (pSer9)
SPC-1384D-A655 0.1ml
EUR 480
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 655.

Antibody for Human GSK3b (pSer9)
SPC-1384D-A680 0.1ml
EUR 480
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 680.

Antibody for Human GSK3b (pSer9)
SPC-1384D-A700 0.1ml
EUR 480
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 700.

Antibody for Human GSK3b (pSer9)
SPC-1384D-ALP 0.1ml
EUR 472.8
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Alkaline Phosphatase.

Antibody for Human GSK3b (pSer9)
SPC-1384D-APC 0.1ml
EUR 478.8
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to APC .

Antibody for Human GSK3b (pSer9)
SPC-1384D-APCCY7 0.1ml
EUR 565.2
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to APC/Cy7.

Antibody for Human GSK3b (pSer9)
SPC-1384D-BI 0.1ml
EUR 475.2
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Biotin.

Antibody for Human GSK3b (pSer9)
SPC-1384D-DY350 0.1ml
EUR 496.8
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Dylight 350.

Antibody for Human GSK3b (pSer9)
SPC-1384D-DY405 0.1ml
EUR 483.6
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Dylight 405.

Antibody for Human GSK3b (pSer9)
SPC-1384D-DY488 0.1ml
EUR 471.6
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Dylight 488.

Antibody for Human GSK3b (pSer9)
SPC-1384D-DY594 0.1ml
EUR 474
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Dylight 594.

Antibody for Human GSK3b (pSer9)
SPC-1384D-DY633 0.1ml
EUR 468
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Dylight 633.

Antibody for Human GSK3b (pSer9)
SPC-1384D-FITC 0.1ml
EUR 470.4
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to FITC.

Antibody for Human GSK3b (pSer9)
SPC-1384D-HRP 0.1ml
EUR 465.6
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to HRP.

Antibody for Human GSK3b (pSer9)
SPC-1384D-P594 0.1ml
EUR 488.4
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to PE/ATTO 594.

Antibody for Human GSK3b (pSer9)
SPC-1384D-PCP 0.1ml
EUR 478.8
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to PerCP.

Antibody for Human GSK3b (pSer9)
SPC-1384D-RPE 0.1ml
EUR 476.4
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to RPE .

Antibody for Human GSK3b (pSer9)
SPC-1384D-STR 0.1ml
EUR 477.6
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Streptavidin.

GSK3B Polyclonal Conjugated Antibody
C30706 100ul
EUR 476.4

[KO Validated] GSK3B Polyclonal Antibody
30706-100ul 100ul
EUR 302.4

[KO Validated] GSK3B Polyclonal Antibody
30706-50ul 50ul
EUR 224.4

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
20-abx318062
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
abx233673-100ug 100 ug
EUR 577.2

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
abx233674-100ug 100 ug
EUR 577.2

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
abx233675-100ug 100 ug
EUR 661.2

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
abx233676-100ug 100 ug
EUR 610.8

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
abx224101-100ug 100 ug
EUR 493.2

Glycogen Synthase Kinase 3 Beta (GSK3b) Antibody
20-abx176674
  • EUR 510.00
  • EUR 159.60
  • EUR 1446.00
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Glycogen Synthase Kinase 3 Beta (GSK3b) Antibody
20-abx176675
  • EUR 1562.40
  • EUR 744.00
  • 1 mg
  • 200 ug

Glycogen Synthase Kinase 3 Beta (GSK3b) Antibody
20-abx172635
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

Glycogen Synthase Kinase 3 Beta (GSK3b) Antibody
20-abx172636
  • EUR 1095.60
  • EUR 560.40
  • 1 mg
  • 200 ug

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
abx147405-100ug 100 ug
EUR 526.8

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
abx332790-100ul 100 ul
EUR 510

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
20-abx330217
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
abx332014-100ul 100 ul
EUR 510

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
20-abx112808
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Glycogen Synthase Kinase 3 Beta (Gsk3b) Antibody
abx028354-400ul 400 ul
EUR 627.6

Glycogen Synthase Kinase 3 Beta (Gsk3b) Antibody
abx028354-80l 80 µl
EUR 343.2

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
abx037712-100ug 100 ug
EUR 469.2

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
20-abx125048
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
20-abx125336
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
20-abx125917
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
20-abx328988
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
20-abx329709
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
20-abx001694
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
20-abx002277
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
20-abx004714
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody
abx010856-100ul 100 ul
EUR 493.2

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody
20-abx134166
  • EUR 427.20
  • EUR 644.40
  • EUR 260.40
  • 100 ul
  • 200 ul
  • 30 ul

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody
20-abx121488
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody
20-abx445135
  • EUR 560.40
  • EUR 360.00
  • 100 ug
  • 25 ug

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody
abx033884-400ul 400 ul
EUR 627.6

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody
abx033884-80l 80 µl
EUR 343.2

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody
20-abx000728
  • EUR 594.00
  • EUR 427.20
  • 100 ul
  • 50 ul

GSK3B Polyclonal Antibody, HRP Conjugated
A62707
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

GSK3B Polyclonal Antibody, FITC Conjugated
A62708
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Phospho-GSK3A/GSK3B (Y279/216) Antibody
1-CSB-PA000535
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Phospho-GSK3A/GSK3B (Y279/216). Recognizes Phospho-GSK3A/GSK3B (Y279/216) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

Rabbit Anti-Human GSK3B Polyclonal Antibody, Phospho-Tyr216
CPB-820RH 100 ul
EUR 670.8

Anti-Glycogen synthase kinase 3 B (GSK3B) (Ser9) antibody
STJ120111 100 µl
EUR 631.2

GSK3B Polyclonal Antibody, Biotin Conjugated
A62709
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Phospho-GSK3A/GSK3B (Tyr279/216) Antibody
CSB-PA575559- each
EUR 402
Description: A polyclonal antibody against Phospho-GSK3A/GSK3B (Tyr279/216). Recognizes Phospho-GSK3A/GSK3B (Tyr279/216) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

Phospho-GSK3A/GSK3B (Tyr279/216) Antibody
CSB-PA575559-100ul 100ul
EUR 434.4
Description: A polyclonal antibody against Phospho-GSK3A/GSK3B (Tyr279/216). Recognizes Phospho-GSK3A/GSK3B (Tyr279/216) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

Rabbit Anti-GSK3A, GSK3B monoclonal antibody, clone TZ37-16
CABT-L635 100 ul
EUR 932.4

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody (HRP)
20-abx304084
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody (ALP)
abx445506-100ug 100 ug
EUR 610.8

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody (APC)
abx445507-100ug 100 ug
EUR 627.6

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody (RPE)
abx445513-100ug 100 ug
EUR 627.6

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody (FITC)
20-abx304085
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody (PerCP)
abx445512-100ug 100 ug
EUR 627.6

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody (Biotin)
20-abx304086
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Polyclonal GSK3B / GSK3 Beta Antibody (C-Terminus)
AMM05222G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human GSK3B / GSK3 Beta (C-Terminus). This antibody is tested and proven to work in the following applications:

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody (ATTO 390)
abx445498-100ug 100 ug
EUR 627.6

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody (ATTO 488)
abx445499-100ug 100 ug
EUR 627.6

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody (ATTO 565)
abx445500-100ug 100 ug
EUR 627.6

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody (ATTO 594)
abx445501-100ug 100 ug
EUR 627.6

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody (ATTO 633)
abx445502-100ug 100 ug
EUR 627.6

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody (ATTO 655)
abx445503-100ug 100 ug
EUR 627.6

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody (ATTO 680)
abx445504-100ug 100 ug
EUR 627.6

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody (ATTO 700)
abx445505-100ug 100 ug
EUR 627.6

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody (Streptavidin)
abx445514-100ug 100 ug
EUR 627.6

Glycogen synthase kinase-3 beta Antibody / GSK3B
RQ7291 100ug
EUR 419

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody (PE/ATTO 594)
abx445511-100ug 100 ug
EUR 644.4

Glycogen Synthase Kinase 3 Beta (GSK3b) Polyclonal Antibody (Human)
4-PAD317Hu01
  • EUR 296.40
  • EUR 3012.00
  • EUR 750.00
  • EUR 372.00
  • EUR 256.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glycogen Synthase Kinase 3 Beta (GSK3b)

GSK3B siRNA
20-abx918789
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

GSK3B siRNA
20-abx918790
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

GSK3B siRNA
20-abx902344
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

GSK3B Plasmid
PVT7113 2 ug
EUR 319.2

Glycogen Synthase Kinase 3 Beta Phospho-Ser9 (GSK3B pS9) Antibody
abx333187-100ul 100 ul
EUR 560.4

Glycogen Synthase Kinase 3 Beta Phospho-Ser9 (GSK3B pS9) Antibody
20-abx328236
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Glycogen Synthase Kinase 3 Beta Phospho-Ser9 (GSK3B pS9) Antibody
20-abx329723
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Glycogen Synthase Kinase-3 Beta Phospho-Ser9 (GSK3B pS9) Antibody
abx411895-01ml 0.1 ml
EUR 844.8

Glycogen Synthase Kinase 3 Beta (GSK3b) Polyclonal Antibody (Human), PE
4-PAD317Hu01-PE
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glycogen Synthase Kinase 3 Beta (GSK3b). This antibody is labeled with PE.

Glycogen Synthase Kinase 3 Beta (GSK3b) Polyclonal Antibody (Human), APC
4-PAD317Hu01-APC
  • EUR 414.00
  • EUR 3930.00
  • EUR 1094.40
  • EUR 528.00
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glycogen Synthase Kinase 3 Beta (GSK3b). This antibody is labeled with APC.

Glycogen Synthase Kinase 3 Beta (GSK3b) Polyclonal Antibody (Human), Cy3
4-PAD317Hu01-Cy3
  • EUR 502.80
  • EUR 5190.00
  • EUR 1410.00
  • EUR 654.00
  • EUR 301.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glycogen Synthase Kinase 3 Beta (GSK3b). This antibody is labeled with Cy3.

Glycogen Synthase Kinase 3 Beta (GSK3b) Polyclonal Antibody (Human), HRP
4-PAD317Hu01-HRP
  • EUR 379.20
  • EUR 3426.00
  • EUR 968.40
  • EUR 477.60
  • EUR 247.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glycogen Synthase Kinase 3 Beta (GSK3b). This antibody is labeled with HRP.

Glycogen Synthase Kinase 3 Beta (GSK3b) Polyclonal Antibody (Human), FITC
4-PAD317Hu01-FITC
  • EUR 355.20
  • EUR 3168.00
  • EUR 900.00
  • EUR 446.40
  • EUR 234.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glycogen Synthase Kinase 3 Beta (GSK3b). This antibody is labeled with FITC.

pT7- His- GSK3B
PVT10128 2 ug
EUR 361.2

Glycogen Synthase Kinase 3 Beta (GSK3b) Polyclonal Antibody (Human), APC-Cy7
4-PAD317Hu01-APC-Cy7
  • EUR 685.20
  • EUR 7716.00
  • EUR 2046.00
  • EUR 912.00
  • EUR 382.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glycogen Synthase Kinase 3 Beta (GSK3b). This antibody is labeled with APC-Cy7.

Glycogen Synthase Kinase 3 Beta (GSK3b) Polyclonal Antibody (Human), Biotinylated
4-PAD317Hu01-Biotin
  • EUR 373.20
  • EUR 2952.00
  • EUR 872.40
  • EUR 457.20
  • EUR 262.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Glycogen Synthase Kinase 3 Beta (GSK3b). This antibody is labeled with Biotin.

GSK3B Rabbit mAb
A10877-100ul 100 ul
EUR 460.8

GSK3B Rabbit mAb
A10877-200ul 200 ul
EUR 664.8

GSK3B Rabbit mAb
A10877-20ul 20 ul Ask for price

GSK3B Rabbit mAb
A10877-50ul 50 ul
EUR 318

GSK3B Rabbit pAb
A11360-100ul 100 ul
EUR 369.6

GSK3B Rabbit pAb
A11360-200ul 200 ul
EUR 550.8

GSK3B Rabbit pAb
A11360-20ul 20 ul
EUR 219.6

GSK3B Rabbit pAb
A11360-50ul 50 ul
EUR 267.6

GSK3B Rabbit pAb
A11578-100ul 100 ul
EUR 369.6

GSK3B Rabbit pAb
A11578-200ul 200 ul
EUR 550.8

GSK3B Rabbit pAb
A11578-20ul 20 ul
EUR 219.6

GSK3B Rabbit pAb
A11578-50ul 50 ul
EUR 267.6

GSK3B Rabbit pAb
A16868-100ul 100 ul
EUR 369.6

GSK3B Rabbit pAb
A16868-200ul 200 ul
EUR 550.8

GSK3B Rabbit pAb
A16868-20ul 20 ul
EUR 219.6

GSK3B Rabbit pAb
A16868-50ul 50 ul
EUR 267.6

GSK3B Rabbit pAb
A3174-100ul 100 ul
EUR 369.6

GSK3B Rabbit pAb
A3174-200ul 200 ul
EUR 550.8

GSK3B Rabbit pAb
A3174-20ul 20 ul
EUR 219.6

GSK3B Rabbit pAb
A3174-50ul 50 ul
EUR 267.6

GSK3B Rabbit pAb
A2081-100ul 100 ul
EUR 369.6

GSK3B Rabbit pAb
A2081-200ul 200 ul
EUR 550.8

GSK3B Rabbit pAb
A2081-20ul 20 ul
EUR 219.6

GSK3B Rabbit pAb
A2081-50ul 50 ul
EUR 267.6

GSK3B cloning plasmid
CSB-CL009963HU-10ug 10ug
EUR 568.8
Description: A cloning plasmid for the GSK3B gene.

GSK3B Blocking Peptide
BF0695-BP 1mg
EUR 234

GSK3b Blocking Peptide
33R-10782 50 ug
EUR 229.2
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of GSK3b antibody, catalog no. 70R-11869

GSK3B Blocking Peptide
DF7231-BP 1mg
EUR 234

Recombinant Human GSK3B
P0221 100ug
EUR 626.83
Description: Recombinant Human protein for GSK3B

pECMV- 3*Flag- GSK3B
PVT10270 2 ug
EUR 361.2

GSK3B protein (His tag)
80R-3636 50 ug
EUR 522
Description: Purified recombinant GSK3B protein (His tag)

Human GSK3B ELISA Kit
ELA-E2298h 96 Tests
EUR 988.8

Rat GSK3B shRNA Plasmid
20-abx986899
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Human GSK3B shRNA Plasmid
20-abx951981
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse GSK3B shRNA Plasmid
20-abx974854
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

GSK3B Recombinant Protein (Rat)
RP203810 100 ug Ask for price

GSK3B Recombinant Protein (Mouse)
RP140201 100 ug Ask for price

GSK3B Recombinant Protein (Human)
RP061362 100 ug Ask for price

Gsk3b ORF Vector (Rat) (pORF)
ORF067938 1.0 ug DNA
EUR 607.2

GSK-3b Antibody
3494-100 each
EUR 392.4

GSK-3b Antibody
3494-30T each
EUR 175.2

GSK3B ORF Vector (Human) (pORF)
ORF020455 1.0 ug DNA
EUR 486

Gsk3b ORF Vector (Mouse) (pORF)
ORF046735 1.0 ug DNA
EUR 607.2

[KO Validated] GSK3B Rabbit pAb
A6164-100ul 100 ul
EUR 492

[KO Validated] GSK3B Rabbit pAb
A6164-200ul 200 ul
EUR 685.2

[KO Validated] GSK3B Rabbit pAb
A6164-20ul 20 ul
EUR 265.2

[KO Validated] GSK3B Rabbit pAb
A6164-50ul 50 ul
EUR 344.4

GSK3B ELISA Kit (Rat) (OKEH03023)
OKEH03023 96 Wells
EUR 841.2
Description: Description of target: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Requires primed phosphorylation of the majority of its substrates. In skeletal muscle, contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. May also mediate the development of insulin resistance by regulating activation of transcription factors. Regulates protein synthesis by controlling the activity of initiation factor 2B (EIF2BE/EIF2B5) in the same manner as glycogen synthase. In Wnt signaling, GSK3B forms a multimeric complex with APC, AXIN1 and CTNNB1/beta-catenin and phosphorylates the N-terminus of CTNNB1 leading to its degradation mediated by ubiquitin/proteasomes. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates NFATC1/NFATC on conserved serine residues promoting NFATC1/NFATC nuclear export, shutting off NFATC1/NFATC gene regulation, and thereby opposing the action of calcineurin. Phosphorylates MAPT/TAU on 'Thr-548', decreasing significantly MAPT/TAU ability to bind and stabilize microtubules. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Phosphorylates MACF1, inhibiting its binding to microtubules which is critical for its role in bulge stem cell migration and skin wound repair. Probably regulates NF-kappa-B (NFKB1) at the transcriptional level and is required for the NF-kappa-B-mediated anti-apoptotic response to TNF-alpha (TNF/TNFA). Negatively regulates replication in pancreatic beta-cells, resulting in apoptosis, loss of beta-cells. Through phosphorylation of the anti-apoptotic protein MCL1, may control cell apoptosis in response to growth factors deprivation. Phosphorylates MUC1 in breast cancer cells, decreasing the interaction of MUC1 with CTNNB1/beta-catenin. Is necessary for the establishment of neuronal polarity and axon outgrowth. Phosphorylates MARK2, leading to inhibit its activity. Phosphorylates SIK1 at 'Thr-182', leading to sustain its activity. Phosphorylates ZC3HAV1 which enhances its antiviral activity. Phosphorylates SFPQ upon T-cell activation. Phosphorylates SNAI1, leading to its BTRC-triggered ubiquitination and proteasomal degradation. Phosphorylates NR1D1 st 'Ser-55' and 'Ser-59' and stabilizes it by protecting it from proteasomal degradation. Regulates the circadian clock via phosphorylation of the major clock components including ARNTL/BMAL1, CLOCK and PER2. Phosphorylates CLOCK AT 'Ser-427' and targets it for proteasomal degradation. Phosphorylates ARNTL/BMAL1 at 'Ser-17' and 'Ser-21' and primes it for ubiquitination and proteasomal degradation. Phosphorylates OGT at 'Ser-3' or 'Ser-4' which positively regulates its activity.3 Publications;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.172 ng/mL

GSK3B ELISA Kit (Human) (OKCD08452)
OKCD08452 96 Wells
EUR 1170
Description: Description of target: Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms, alpha (GSK3A) and beta, show a high degree of amino acid homology. GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation.Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms, alpha (GSK3A; MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994.). GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation (Plyte et al., 1992.)... Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.227ng/mL
Constantly, over-expression of a constitutively energetic GSK enhanced Ang II-induced ET1 transcription and knockdown of both MRTF-A or BRG1 abrogated the enhancement of ET1 transcription. In conclusion, our information spotlight a beforehand unrecognized mechanism that contributes to the transcriptional regulation of endothelin. Concentrating on this GSK3-SRF axis could yield novel approaches within the intervention of cardiovascular ailments.
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TCF/LEF regulation of the topologically associated domain ADI promotes mESCs to exit the pluripotent ground state
Identification of Potential Kinase Inhibitors within the PI3K/AKT Pathway of Leishmania Species

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