Unravelling the selectivity of 6,7 dimethyl Quinoxaline analogues for kinase inhibition: An Insight towards the development of Alzheimer's therapeutics

Unravelling the selectivity of 6,7 dimethyl Quinoxaline analogues for kinase inhibition: An Insight towards the development of Alzheimer’s therapeutics

Untangling probably the most selective kinase inhibitors by way of pharmacological intervention stays one of many difficult affairs thus far. Inaccordance to this drift, herein we describe the design and synthesis of a set of recent heterocyclic analogues consisting of 6,7 dimethyl Quinoxaline, appended to a connector, using Schiff base technique (Compounds I – IX ).
The compounds had been characterised by numerous spectroscopic strategies and the kinase inhibition assay had been carried out on few prime members of the CMGC household specifically the GSK3 b , DYRK1A and CLK1 receptors respectively, which were identified to be straight concerned in hyperphosphorylation of Tau.
Curiously the organic analysis outcomes revealed that Compounds IV & V , with bromo/chloro functionalities within the fragrant core had been advantaged of being extremely selective in the direction of the goal GSK3b over others.
To strengthen our evaluation, we adopted molecular modelling research, the place compounds IV /V had been redocked in the identical grid 4AFJ, as that of the reference ligand, 5-Aryl-4-Carboxamide-1,3-Oxazole. Surprisingly, our investigation underpined that for each the compounds IV/V, a major H-bonding existed between the designed molecules ( IV/V) and Val 135 residue within the receptor GSK3b, inline with the reference ligand. We attribute this interplay to instigate efficiency within the compounds.
Certainly the opposite non-covalent interplay, between the by-product’s fragrant nucleus and Arg 141/Thr 138 within the receptor GSK3b, might need been answerable for enhancing the selectivity within the targets. Total, we really feel that the current work depicts a logical demonstration in the direction of advantageous tuning the efficacy of the inhibitors by way of systematic adjustment of electron density at acceptable positions within the fragrant ring be it the primary quinoxaline or the opposite fragrant nucleus. Thus this pathway presents a handy technique for the event of environment friendly therapeutics for diversified neurodegenerative ailments like that of Alzheimer’s.

GSK3 as a Regulator of Cytoskeleton Structure: Penalties for Well being and Illness

Glycogen synthase kinase 3 (GSK3) was initially remoted as a vital protein in vitality metabolism. Nonetheless, subsequent research point out that GSK-Three is a multi-tasking kinase that hyperlinks quite a few signaling pathways in a cell and performs an important position within the regulation of many elements of mobile physiology.
As a regulator of actin and tubulin cytoskeleton, GSK3 influences processes of cell polarization, interplay with the extracellular matrix, and directional migration of cells and their organelles throughout the progress and growth of an animal organism. On this assessment, the roles of GSK3-cytoskeleton interactions in mind growth and pathology, migration of wholesome and most cancers cells, and in mobile trafficking of mitochondria shall be mentioned.
Unravelling the selectivity of 6,7 dimethyl Quinoxaline analogues for kinase inhibition: An Insight towards the development of Alzheimer's therapeutics

An Overview of the Security, Effectivity, and Sign Pathways of Stem Cell Remedy for Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune illness that impacts a number of organs and tissues. Mesenchymal stem cells (MSCs) are thought-about a great supply for autoimmune illness and hematological illness remedy. This assessment will summarize the efficacy, security, and mechanisms of MSC remedy for SLE.
MSC remedy can scale back anti-dsDNA, antinuclear antigen (ANA), proteinuria, and serum creatinine in SLE sufferers. In animal fashions of SLE, MSC remedy additionally signifies that it might scale back anti-dsDNA, ANA, proteinuria, and serum creatinine and ameliorate renal pathology.
There aren’t any severe hostile occasions, treatment-related mortality, or tumor-related occasions in SLE sufferers after stem cell therapy. MSCs can inhibit inflammatory components, equivalent to MCP-1 and HMGB-1, and inhibit inflammation-related signaling pathways, such because the NF-κB, JAK/STAT, and Akt/GSK3β signaling pathways, to alleviate the lesions in SLE.

Mitotic WNT signalling orchestrates neurogenesis within the growing neocortex

The position of WNT/β-catenin signalling in mouse neocortex growth stays ambiguous. Most research reveal that WNT/β-catenin regulates progenitor self-renewal however others counsel it could additionally promote differentiation. Right here we discover the position of WNT/STOP signalling, which stabilizes proteins throughout G2/M by inhibiting glycogen synthase kinase (GSK3)-mediated protein degradation.
We present that mice mutant for cyclin Y and cyclin Y-like 1 (Ccny/l1), key regulators of WNT/STOP signalling, show decreased neurogenesis within the growing neocortex. Particularly, basal progenitors, which exhibit delayed cell cycle development, had been drastically decreased. Ccny/l1-deficient apical progenitors present decreased uneven division attributable to a rise in apical-basal astral microtubules.
We establish the neurogenic transcription components Sox4 and Sox11 as direct GSK3 targets which are stabilized by WNT/STOP signalling in basal progenitors throughout mitosis and that promote neuron technology. Our work reveals that WNT/STOP signalling drives cortical neurogenesis and identifies mitosis as a vital part for neural progenitor destiny.

GSK3s: nodes of multilayer regulation of plant growth and stress responses

Glycogen synthase kinase 3 (GSK3) relations are extremely conserved serine/threonine protein kinases in eukaryotes. Not like animals, vegetation have developed with a number of homologs of GSK3s concerned in a various array of organic processes. Rising proof means that GSK3s act as signaling hubs for integrating notion and transduction of numerous indicators required for plant growth and responses to abiotic and biotic cues.
Right here we assessment current advances in understanding the molecular interactions between GSK3s and an increasing spectrum of their upstream regulators and downstream substrates in vegetation. We additional focus on how GSK3s act as key signaling nodes of multilayer regulation of plant growth and stress response by way of both being regulated on the post-translational degree or regulating their substrates by way of phosphorylation.

GSK3-SRF Axis Mediates Angiotensin II Induced Endothelin Transcription in Vascular Endothelial Cells

Endothelin, encoded by ET1, is a vasoactive substance primarily synthesized in vascular endothelial cells (VECs). Elevation of endothelin ranges, attributable to transcriptional hyperactivation, has been noticed in a bunch of cardiovascular ailments. We now have beforehand proven that serum response issue (SRF) is a regulator of ET1 transcription in VECs.
Right here we report that angiotensin II (Ang II) induced ET1 transcription paralleled activation of glycogen synthase kinase 3 (GSK3) in cultured VECs. GSK3 knockdown or pharmaceutical inhibition attenuated Ang II induced endothelin expression.
Unravelling the selectivity of 6,7 dimethyl Quinoxaline analogues for kinase inhibition: An Insight towards the development of Alzheimer's therapeutics
Of curiosity, the impact of GSK3 on endothelin transcription relied on the conserved SRF motif inside the ET1 promoter. Additional evaluation revealed that GSK3 interacted with and phosphorylated SRF at serine 224. Phosphorylation of SRF by GSK3 didn’t affect its recruitment to the ET1 promoter.
As an alternative, GSK3-mediated SRF phosphorylation potentiated its interplay with MRTF-A, a key co-factor for SRF, which helped recruit the chromatin transforming protein BRG1 to the ET1 promoter leading to augmented histone H3 acetylation/H3K4 trimethylation.

Anti-GSK3B antibody

STJ113773 100 µl
EUR 332.4
Description: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-GSK3B antibody

STJ113841 100 µl
EUR 332.4
Description: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-GSK3B antibody

STJ23879 100 µl
EUR 332.4
Description: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-GSK3B antibody

STJ23880 100 µl
EUR 332.4
Description: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-GSK3B antibody

STJ27912 100 µl
EUR 495.6
Description: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-GSK3B Antibody

STJ501295 100 µg
EUR 571.2

Anti-GSK3B antibody

STJ119229 100 µl
EUR 332.4

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 418.8

Anti-GSK3B Antibody (Biotin)

STJ501296 100 µg
EUR 703.2

Anti-GSK3B Antibody (FITC)

STJ501297 100 µg
EUR 703.2

Human Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

DLR-GSK3b-Hu-48T 48T
EUR 620.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Glycogen Synthase Kinase 3 Beta (GSK3b) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

DLR-GSK3b-Hu-96T 96T
EUR 807.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Glycogen Synthase Kinase 3 Beta (GSK3b) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

DLR-GSK3b-Mu-48T 48T
EUR 632.4
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Glycogen Synthase Kinase 3 Beta (GSK3b) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

DLR-GSK3b-Mu-96T 96T
EUR 825.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Glycogen Synthase Kinase 3 Beta (GSK3b) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

DLR-GSK3b-Ra-48T 48T
EUR 658.8
Description: A sandwich quantitative ELISA assay kit for detection of Rat Glycogen Synthase Kinase 3 Beta (GSK3b) in samples from tissue homogenates, cell lysates or other biological fluids.

Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

DLR-GSK3b-Ra-96T 96T
EUR 861.6
Description: A sandwich quantitative ELISA assay kit for detection of Rat Glycogen Synthase Kinase 3 Beta (GSK3b) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

RD-GSK3b-Hu-48Tests 48 Tests
EUR 625.2

Human Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

RD-GSK3b-Hu-96Tests 96 Tests
EUR 867.6

Mouse Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

RD-GSK3b-Mu-48Tests 48 Tests
EUR 639.6

Mouse Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

RD-GSK3b-Mu-96Tests 96 Tests
EUR 888

Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

RD-GSK3b-Ra-48Tests 48 Tests
EUR 668.4

Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

RD-GSK3b-Ra-96Tests 96 Tests
EUR 930

Human Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

RDR-GSK3b-Hu-48Tests 48 Tests
EUR 652.8

Human Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

RDR-GSK3b-Hu-96Tests 96 Tests
EUR 907.2

Mouse Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

RDR-GSK3b-Mu-48Tests 48 Tests
EUR 668.4

Mouse Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

RDR-GSK3b-Mu-96Tests 96 Tests
EUR 928.8

Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

RDR-GSK3b-Ra-48Tests 48 Tests
EUR 699.6

Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit

RDR-GSK3b-Ra-96Tests 96 Tests
EUR 973.2

anti-GSK3B (3D10)

LF-MA30340 100 ul
EUR 583.2
Description: Mouse Monoclonal to GSK3B

Anti-GSK3b (Ab-9) Antibody

A00791-1 100ul
EUR 476.4
Description: Rabbit Polyclonal GSK3b (Ab-9) Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Phospho-GSK3B-(Y216) antibody

STJ110852 100 µl
EUR 471.6
Description: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Phospho-GSK3B-(S9) antibody

STJ22160 100 µl
EUR 471.6
Description: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-Phospho-GSK3B-(Y216) antibody

STJ116370 100 µl
EUR 471.6
Description: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

GSK3B Antibody

1-CSB-PA002848
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IP, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IP:2-5ug/mglysate.ELISA:1/20000

GSK3B Antibody

1-CSB-PA080166
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC;WB:1:1000-2000.IHC:1:200-500

GSK3B Antibody

1-CSB-PA009963GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human, Mouse, Rat, Pig. This antibody is Unconjugated. Tested in the following application: ELISA, WB

GSK3B Antibody

1-CSB-PA009963LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF; Recommended dilution: WB:1:2000-1:10000, IF:1:50-1:500

GSK3B Antibody

1-CSB-PA009038
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/5000

GSK3B Antibody

CSB-PA939628-
EUR 402
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

GSK3B Antibody

CSB-PA939628-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

GSK3b antibody

70R-11869 100 ug
EUR 501.6
Description: Rabbit polyclonal GSK3b antibody

GSK3B antibody

70R-17615 50 ul
EUR 522
Description: Rabbit polyclonal GSK3B antibody

GSK3B antibody

70R-15005 100 ul
EUR 470.4
Description: Rabbit polyclonal GSK3B antibody

GSK3B Antibody

36918-100ul 100ul
EUR 302.4

GSK3B antibody

38353-100ul 100ul
EUR 302.4

GSK3B antibody

38616-100ul 100ul
EUR 302.4

GSK3B antibody

10R-1862 100 ul
EUR 483.6
Description: Mouse monoclonal GSK3B antibody

GSK3B Antibody

ABD6806 100 ug
EUR 525.6

GSK3B Antibody

ABD7231 100 ug
EUR 525.6

GSK3B Antibody

BF0695 200ul
EUR 540

GSK3B Antibody

F51046-0.08ML 0.08 ml
EUR 165

GSK3B Antibody

F51046-0.4ML 0.4 ml
EUR 379

Gsk3b Antibody

F44221-0.08ML 0.08 ml
EUR 165

Gsk3b Antibody

F44221-0.4ML 0.4 ml
EUR 379

GSK3A/GSK3B Antibody

1-CSB-PA002838
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3A/GSK3B. Recognizes GSK3A/GSK3B from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

GSK3B Conjugated Antibody

C36918 100ul
EUR 476.4

GSK3B Conjugated Antibody

C38353 100ul
EUR 476.4

Phospho-GSK3b antibody

70R-11870 100 ug
EUR 630
Description: Rabbit polyclonal Phospho-GSK3b antibody

GSK3B (pY216) Antibody

20-abx123289
  • EUR 594.00
  • EUR 844.80
  • EUR 260.40
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

GSK3B (pY216) Antibody

20-abx000312
  • EUR 594.00
  • EUR 844.80
  • EUR 260.40
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

GSK3A / GSK3B Antibody

20-abx328487
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

GSK3B Polyclonal Antibody

A72446-050 50 ul
EUR 302.5

GSK3B Polyclonal Antibody

A72446-100 100 ul
EUR 423.5

GSK3B Polyclonal Antibody

A72447-050 50 ul
EUR 302.5

GSK3B Polyclonal Antibody

A72447-100 100 ul
EUR 423.5

GSK3B Polyclonal Antibody

A72448-050 50 ul
EUR 302.5

GSK3B Polyclonal Antibody

A72448-100 100 ul
EUR 423.5

GSK3B Polyclonal Antibody

A72450-050 50 ul
EUR 377.3

GSK3B Polyclonal Antibody

A72450-100 100 ul
EUR 577.5

GSK3B Polyclonal Antibody

A62706-020 20 ul
EUR 117.7

GSK3B Polyclonal Antibody

A62706-050 50 ul
EUR 302.5

GSK3B Polyclonal Antibody

A62706-100 100 ul
EUR 423.5

GSK3B Polyclonal Antibody

A62706
  • EUR 684.66
  • EUR 117.70
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

GSK3B Polyclonal Antibody

A72446
  • EUR 302.50
  • EUR 423.50
  • 50 ul
  • 100 ul

GSK3B Polyclonal Antibody

A72447
  • EUR 302.50
  • EUR 423.50
  • 50 ul
  • 100 ul

GSK3B Polyclonal Antibody

A72448
  • EUR 302.50
  • EUR 423.50
  • 50 ul
  • 100 ul

GSK3B Polyclonal Antibody

A72450
  • EUR 377.30
  • EUR 577.50
  • 50 ul
  • 100 ul

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 336

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 336

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 336

GSK3B siRNA

20-abx918789
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

GSK3B siRNA

20-abx918790
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

GSK3B siRNA

20-abx902344
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

GSK3B Plasmid

PVT7113 2 ug
EUR 319.2

Phospho-GSK3B (Ser9) Antibody

CSB-PA166926-
EUR 402
Description: A polyclonal antibody against Phospho-GSK3B (Ser9). Recognizes Phospho-GSK3B (Ser9) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

Phospho-GSK3B (Ser9) Antibody

CSB-PA166926-100ul 100ul
EUR 434.4
Description: A polyclonal antibody against Phospho-GSK3B (Ser9). Recognizes Phospho-GSK3B (Ser9) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

GSK3B (Ab-9) Antibody

CSB-PA120951-
EUR 402
Description: A polyclonal antibody against GSK3B (Ab-9). Recognizes GSK3B (Ab-9) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

GSK3B (Ab-9) Antibody

CSB-PA120951-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against GSK3B (Ab-9). Recognizes GSK3B (Ab-9) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

GSK3B Antibody, HRP conjugated

1-CSB-PA009963LB01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

GSK3B Antibody, FITC conjugated

1-CSB-PA009963LC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

GSK3B Antibody, Biotin conjugated

1-CSB-PA009963LD01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GSK3B. Recognizes GSK3B from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Phospho-GSK3B (S9) Antibody

1-CSB-PA000536
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Phospho-GSK3B (S9). Recognizes Phospho-GSK3B (S9) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IP, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IP:2-5ug/mglysate.ELISA:1/5000

Phospho-GSK3B (S9) Antibody

1-CSB-PA000636
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Phospho-GSK3B (S9). Recognizes Phospho-GSK3B (S9) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/10000

GSK3B Polyclonal Conjugated Antibody

C30706 100ul
EUR 476.4

GSK3B (pS21 / 29) Antibody

abx031864-400ul 400 ul
EUR 627.6

GSK3B (pS21 / 29) Antibody

abx031864-80l 80 µl
EUR 343.2

GSK3 beta Antibody / GSK3B

F54007-0.1ML 0.1 ml
EUR 379

Rabbit Anti-Human GSK3B Polyclonal Antibody, Phospho-Tyr216

CPB-820RH 100 ul
EUR 670.8

Rabbit Anti-GSK3B monoclonal antibody, clone TZ13-82

DCABH-9320 100 ul
EUR 932.4

GSK3B Blocking Peptide

DF7231-BP 1mg
EUR 234

GSK3B cloning plasmid

CSB-CL009963HU-10ug 10ug
EUR 568.8
Description: A cloning plasmid for the GSK3B gene.

GSK3B Rabbit pAb

A11360-100ul 100 ul
EUR 369.6

GSK3B Rabbit pAb

A11360-200ul 200 ul
EUR 550.8

GSK3B Rabbit pAb

A11360-20ul 20 ul
EUR 219.6

GSK3B Rabbit pAb

A11360-50ul 50 ul
EUR 267.6

GSK3B Rabbit pAb

A11578-100ul 100 ul
EUR 369.6

GSK3B Rabbit pAb

A11578-200ul 200 ul
EUR 550.8

GSK3B Rabbit pAb

A11578-20ul 20 ul
EUR 219.6

GSK3B Rabbit pAb

A11578-50ul 50 ul
EUR 267.6

GSK3B Rabbit mAb

A10877-100ul 100 ul
EUR 460.8

GSK3B Rabbit mAb

A10877-200ul 200 ul
EUR 664.8

GSK3B Rabbit mAb

A10877-20ul 20 ul Ask for price

GSK3B Rabbit mAb

A10877-50ul 50 ul
EUR 318

GSK3b Blocking Peptide

33R-10782 50 ug
EUR 229.2
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of GSK3b antibody, catalog no. 70R-11869

GSK3B Rabbit pAb

A3174-100ul 100 ul
EUR 369.6

GSK3B Rabbit pAb

A3174-200ul 200 ul
EUR 550.8

GSK3B Rabbit pAb

A3174-20ul 20 ul
EUR 219.6

GSK3B Rabbit pAb

A3174-50ul 50 ul
EUR 267.6

GSK3B Rabbit pAb

A2081-100ul 100 ul
EUR 369.6

GSK3B Rabbit pAb

A2081-200ul 200 ul
EUR 550.8

GSK3B Rabbit pAb

A2081-20ul 20 ul
EUR 219.6

GSK3B Rabbit pAb

A2081-50ul 50 ul
EUR 267.6

GSK3B Rabbit pAb

A16868-100ul 100 ul
EUR 369.6

GSK3B Rabbit pAb

A16868-200ul 200 ul
EUR 550.8

GSK3B Rabbit pAb

A16868-20ul 20 ul
EUR 219.6

GSK3B Rabbit pAb

A16868-50ul 50 ul
EUR 267.6

GSK3B Blocking Peptide

BF0695-BP 1mg
EUR 234

Recombinant Human GSK3B

P0221 100ug
EUR 626.83
Description: Recombinant Human protein for GSK3B

pT7- His- GSK3B

PVT10128 2 ug
EUR 361.2

[KO Validated] GSK3B Polyclonal Antibody

30706-100ul 100ul
EUR 302.4

[KO Validated] GSK3B Polyclonal Antibody

30706-50ul 50ul
EUR 224.4

GSK3A / GSK3B (pY279 / 216) Antibody

abx333212-100ul 100 ul
EUR 560.4

GSK3A / GSK3B (pY279 / 216) Antibody

20-abx328488
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Polyclonal GSK3B / GSK3 Beta Antibody

AMM05221G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human GSK3B / GSK3 Beta . This antibody is tested and proven to work in the following applications:

Monoclonal GSK3B Antibody, Clone: 3D6B4

AMM05223G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human GSK3B. The antibodies are raised in Mouse and are from clone 3D6B4. This antibody is applicable in WB and IHC, FC, E

Antibody for Human GSK3b (pSer9)

SPC-1384D 0.1ml
EUR 424.8
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is unconjugated.

Antibody for Human GSK3b (pSer9)

SPC-1384D-A390 0.1ml
EUR 481.2
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 390.

Antibody for Human GSK3b (pSer9)

SPC-1384D-A488 0.1ml
EUR 480
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 488.

Antibody for Human GSK3b (pSer9)

SPC-1384D-A565 0.1ml
EUR 480
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 565.

Antibody for Human GSK3b (pSer9)

SPC-1384D-A594 0.1ml
EUR 480
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 594.

Antibody for Human GSK3b (pSer9)

SPC-1384D-A633 0.1ml
EUR 480
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 633.

Antibody for Human GSK3b (pSer9)

SPC-1384D-A655 0.1ml
EUR 480
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 655.

Antibody for Human GSK3b (pSer9)

SPC-1384D-A680 0.1ml
EUR 480
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 680.

Antibody for Human GSK3b (pSer9)

SPC-1384D-A700 0.1ml
EUR 480
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to ATTO 700.

Antibody for Human GSK3b (pSer9)

SPC-1384D-ALP 0.1ml
EUR 472.8
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Alkaline Phosphatase.

Antibody for Human GSK3b (pSer9)

SPC-1384D-APC 0.1ml
EUR 478.8
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to APC .

Antibody for Human GSK3b (pSer9)

SPC-1384D-APCCY7 0.1ml
EUR 565.2
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to APC/Cy7.

Antibody for Human GSK3b (pSer9)

SPC-1384D-BI 0.1ml
EUR 475.2
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Biotin.

Antibody for Human GSK3b (pSer9)

SPC-1384D-DY350 0.1ml
EUR 496.8
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Dylight 350.

Antibody for Human GSK3b (pSer9)

SPC-1384D-DY405 0.1ml
EUR 483.6
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Dylight 405.

Antibody for Human GSK3b (pSer9)

SPC-1384D-DY488 0.1ml
EUR 471.6
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Dylight 488.

Antibody for Human GSK3b (pSer9)

SPC-1384D-DY594 0.1ml
EUR 474
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Dylight 594.

Antibody for Human GSK3b (pSer9)

SPC-1384D-DY633 0.1ml
EUR 468
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Dylight 633.

Antibody for Human GSK3b (pSer9)

SPC-1384D-FITC 0.1ml
EUR 470.4
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to FITC.

Antibody for Human GSK3b (pSer9)

SPC-1384D-HRP 0.1ml
EUR 465.6
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to HRP.

Antibody for Human GSK3b (pSer9)

SPC-1384D-P594 0.1ml
EUR 488.4
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to PE/ATTO 594.

Antibody for Human GSK3b (pSer9)

SPC-1384D-PCP 0.1ml
EUR 478.8
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to PerCP.

Antibody for Human GSK3b (pSer9)

SPC-1384D-RPE 0.1ml
EUR 476.4
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to RPE .

Antibody for Human GSK3b (pSer9)

SPC-1384D-STR 0.1ml
EUR 477.6
Description: A polyclonal antibody for GSK3b (pSer9) from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with human synthetic phospho-peptide from human GSK3b around the phosphorylation site of serine 9 (pSer9).. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:250-1:1000); IHC (1:25-1:100); IP (Various dilutions). This GSK3b (pSer9) antibody is conjugated to Streptavidin.

Phospho-GSK3B-S9 Polyclonal Antibody

A72451-050 50 ul
EUR 341

Phospho-GSK3B-S9 Polyclonal Antibody

A72451-100 100 ul
EUR 518.1

Phospho-GSK3B-Y216 Polyclonal Antibody

A72452-050 50 ul
EUR 341

Phospho-GSK3B-Y216 Polyclonal Antibody

A72452-100 100 ul
EUR 518.1

GSK3B Polyclonal Antibody, HRP Conjugated

A62707-050 50 ul
EUR 302.5

GSK3B Polyclonal Antibody, HRP Conjugated

A62707-100 100 ul
EUR 423.5

GSK3B Polyclonal Antibody, FITC Conjugated

A62708-050 50 ul
EUR 302.5

GSK3B Polyclonal Antibody, FITC Conjugated

A62708-100 100 ul
EUR 423.5

GSK3B Polyclonal Antibody, Biotin Conjugated

A62709-050 50 ul
EUR 302.5

GSK3B Polyclonal Antibody, Biotin Conjugated

A62709-100 100 ul
EUR 423.5

GSK3B Polyclonal Antibody, HRP Conjugated

A62707
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

GSK3B Polyclonal Antibody, FITC Conjugated

A62708
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

GSK3B Polyclonal Antibody, Biotin Conjugated

A62709
  • EUR 684.66
  • EUR 302.50
  • EUR 423.50
  • 100 µg
  • 50 ul
  • 100 ul

Phospho-GSK3B-S9 Polyclonal Antibody

A72451
  • EUR 341.00
  • EUR 518.10
  • 50 ul
  • 100 ul

Phospho-GSK3B-Y216 Polyclonal Antibody

A72452
  • EUR 341.00
  • EUR 518.10
  • 50 ul
  • 100 ul

Rabbit Anti-GSK3A, GSK3B monoclonal antibody, clone TZ37-16

CABT-L635 100 ul
EUR 932.4

Rabbit Anti-Human GSK3B (aa 214-218) Polyclonal Antibody

CPB-1178RH 100 ul
EUR 552

Anti-Glycogen synthase kinase 3 B (GSK3B) (Ser9) antibody

STJ120111 100 µl
EUR 631.2

GSK3A/GSK3B (Ab-279/216) Antibody

CSB-PA255909-
EUR 402
Description: A polyclonal antibody against GSK3A/GSK3B (Ab-279/216). Recognizes GSK3A/GSK3B (Ab-279/216) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

GSK3A/GSK3B (Ab-279/216) Antibody

CSB-PA255909-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against GSK3A/GSK3B (Ab-279/216). Recognizes GSK3A/GSK3B (Ab-279/216) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Phospho-GSK3A/GSK3B (Y279/216) Antibody

1-CSB-PA000535
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Phospho-GSK3A/GSK3B (Y279/216). Recognizes Phospho-GSK3A/GSK3B (Y279/216) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

Phospho-GSK3A/GSK3B (Tyr279/216) Antibody

CSB-PA575559-
EUR 402
Description: A polyclonal antibody against Phospho-GSK3A/GSK3B (Tyr279/216). Recognizes Phospho-GSK3A/GSK3B (Tyr279/216) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

Phospho-GSK3A/GSK3B (Tyr279/216) Antibody

CSB-PA575559-100ul 100ul
EUR 434.4
Description: A polyclonal antibody against Phospho-GSK3A/GSK3B (Tyr279/216). Recognizes Phospho-GSK3A/GSK3B (Tyr279/216) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

GSK3A / GSK3B (Ab-279 / 216) Antibody

abx332166-100ul 100 ul
EUR 510

Polyclonal Mouse Gsk3b Antibody (N-term)

APR04027G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Mouse Gsk3b (N-term). This antibody is tested and proven to work in the following applications:

Human GSK3B shRNA Plasmid

20-abx951981
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse GSK3B shRNA Plasmid

20-abx974854
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Rat GSK3B shRNA Plasmid

20-abx986899
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

GSK3B protein (His tag)

80R-3636 50 ug
EUR 522
Description: Purified recombinant GSK3B protein (His tag)

Human GSK3B ELISA Kit

ELA-E2298h 96 Tests
EUR 988.8

pcDNA3.1-Myc-GSK3B Plasmid

PVTB01013-2a 2 ug
EUR 427.2

pECMV- 3*Flag- GSK3B

PVT10270 2 ug
EUR 361.2

GSK3B Recombinant Protein (Rat)

RP203810 100 ug Ask for price

GSK3B Recombinant Protein (Human)

RP061362 100 ug Ask for price

GSK3B Recombinant Protein (Mouse)

RP140201 100 ug Ask for price

Glycogen Synthase Kinase 3 Beta (GSK3b) Antibody

20-abx172635
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

Glycogen Synthase Kinase 3 Beta (GSK3b) Antibody

20-abx172636
  • EUR 1095.60
  • EUR 560.40
  • 1 mg
  • 200 ug

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody

abx147405-100ug 100 ug
EUR 526.8

Glycogen Synthase Kinase-3 Beta (GSK3B) Antibody

20-abx121488
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Glycogen Synthase Kinase 3 Beta (GSK3B) Antibody

20-abx125048
  • EUR 594.00
  • EUR 844.80
  • EUR 427.20
  • 100 ul
  • 200 ul
  • 50 ul
Constantly, over-expression of a constitutively energetic GSK enhanced Ang II-induced ET1 transcription and knockdown of both MRTF-A or BRG1 abrogated the enhancement of ET1 transcription. In conclusion, our information spotlight a beforehand unrecognized mechanism that contributes to the transcriptional regulation of endothelin. Concentrating on this GSK3-SRF axis could yield novel approaches within the intervention of cardiovascular ailments.

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