gene tex, The biology, function, and applications of exosomes in cancer

The biology, function, and applications of exosomes in cancer

Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, launched upon fusion of multivesicular our bodies with the cell floor. They will transport nucleic acids, proteins, and lipids for intercellular communication and activate signaling pathways in goal cells.

In cancers, exosomes might take part in development and metastasis of tumors by regulating the immune response, blocking the epithelial-mesenchymal transition, and selling angiogenesis. They’re additionally concerned within the improvement of resistance to chemotherapeutic medicine. Exosomes in liquid biopsies can be utilized as non-invasive biomarkers for early detection and prognosis of cancers. Due to their amphipathic construction, exosomes are pure drug supply autos for most cancers remedy.

Rising Significance and Therapeutic Potential of Extracellular vesicles

Extracellular vesicles (EVs), are membrane-bound vesicles which have many benefits over conventional nanocarriers for drug and gene supply. Proof from latest research point out that EVs have therapeutic functionality with chemical or organic modification. Tumor-derived exosomes (TEXs) have been used as a brand new kind of antigens or tumor vaccines in anti-tumor immunotherapy.
With superior traits, modified EVs have been utilized to loaded and delivered artificial medicine, silencing RNA, and microRNA for remedy. Totally different floor functionalization methods have been proposed to enhance the therapeutic capabilities of EVs.
Appropriately modified EVs for illness intervention present new avenues for efficient scientific remedy methods. Subsequently, this evaluation geared toward elucidating the therapeutic capabilities of EVs to generate new concepts for remedy and to unlock their hidden potential in translational drugs.
gene tex, The biology, function, and applications of exosomes in cancer

Rising Diagnostic Potential of Tumor-derived Exosomes

Exosomes carry genetic info originating from their parental cells, elevating their risk as novel noninvasive biomarkers for most cancers. Tumor-derived exosomes (TEXs) have a wide range of endogenous cargos that mirror the pathophysiology standing and data of tumor cells. TEXs are more and more being acknowledged as potential biomarkers for most cancers prognosis prognosis, and monitoring.
You will need to develop a wide range of delicate strategies, together with probes and biomaterials to isolate exosomes. A wide range of approaches for detecting exosomes have been established. By combining exosome DNA and RNA sequencing instruments, exosome proteomics evaluation and immunoassay know-how, it’s anticipated that exosomes will acquire widespread use within the prognosis and remedy of most cancers.

Improvement and Medical Software of Tumor-derived Exosomes in Sufferers with Most cancers

A tumor is an irregular development of cells inside a tissue that may result in demise as a result of late prognosis, poor prognosis, drug resistance, and eventually enhanced metastasis formation. Exosomes are nanovesicles which have been derived from all of the totally different cell sorts. These vesicles can switch varied molecules, together with the distinct type of nucleic acids (mRNA, miRNA, and circRNA) and proteins.
Tumor-derived exosomes (TEXs) have exceptionally vital roles via a number of molecular and mobile pathways like development, tumorigenesis, drug resistance, and in addition to metastasis. TEXs are detectable in all physique fluids, reminiscent of serum and urine, a handy and non-invasive technique to entry these nano-sized vesicles. TEXs result in the symptom expression of genetic aberrations within the tumor cell inhabitants, making them an correct and delicate biomarker for the prognosis and prognosis of tumors.
Alternatively, TEXs include main histocompatibility complexes (MHCs) and play vital twin roles in regulating tumor immune responses; they will mediate each immune activation and suppression via tumor-associated immunity. Regardless of quite a few scientific research, there are nonetheless many technical limitations to tell apart TEXs from non-tumor-derived exosomes.
Eradicating exosomes result in a large distinction in outcomes inside a affected person’s physique. Therefore, controversial items of proof have demonstrated the very important position of TEXs as hopeful biomarkers for the early detection of cancers, analysis of therapeutic results, and monitoring of the affected person.

Human testis-expressed (TEXgenes: a evaluation targeted on spermatogenesis and male fertility

Spermatogenesis is a fancy course of regulated by a large number of genes. The identification and characterization of male-germ-cell-specific genes is essential to understanding the mechanisms via which the cells develop. The time period “TEX gene” was coined by Wang et al. (Nat Genet. 2001; 27: 422-6) after they used cDNA suppression subtractive hybridization (SSH) to establish new transcripts that have been current solely in purified mouse spermatogonia.
TEX (Testis expressed) orthologues have been present in different vertebrates (mammals, birds, and reptiles), invertebrates, and yeasts. To this point, 69 TEX genes have been described in several species and totally different tissues. To guage the expression of every TEX/tex gene, we compiled knowledge from 7 totally different RNA-Seq mRNA databases in people, and four within the mouse based on the expression atlas database.
Varied research have highlighted a job for a lot of of those genes in spermatogenesis. Right here, we evaluation present information on the TEX genes and their roles in spermatogenesis and fertilization in people and, comparatively, in different species (notably the mouse). As anticipated, TEX genes seem to have a significant position in copy in general and in spermatogenesis in people but in addition in all mammals such because the mouse.
Most of them are expressed particularly or predominantly within the testis. As many of the TEX genes are extremely conserved in mammals, defects within the male (gene mutations in people and gene-null mice) result in infertility. Sooner or later, cumulative knowledge on the human TEX genes‘ physiological capabilities and pathophysiological dysfunctions ought to turn out to be accessible and is prone to verify the important position of this household within the reproductive course of. 13 TEX genes at the moment are referenced within the OMIM database, and three have been linked to a selected phenotype. TEXgene most continuously reported as being related to azoospermia.

Cannabinoid receptor agonists from Conus venoms alleviate pain-related conduct in rats

Cannabinoid (CB) receptor agonists present strong antinociceptive results in varied ache fashions. Nevertheless, many of the clinically potent CB1 receptor-active medicine derived from hashish are thought of regarding as a result of psychotomimetic negative effects. Selective CB receptor ligands that don’t induce CNS negative effects are of scientific curiosity.
The venoms of marine snail Conus are a pure supply of varied potent analgesic peptides, a few of that are already FDA accepted. On this examine we evaluated the power of a number of Conus venom extracts to work together with CB1 receptor. HEK293 cells expressing CB1 receptors have been handled with venom extracts and CB1 receptor internalization was analyzed by immunofluorescence. Outcomes confirmed C. textile (C. Tex) and C. miles (C. Mil) samples as probably the most potent.
These have been serially subfractionated by HPLC for subsequent evaluation by internalization assays and for analgesic efficiency evaluated within the formalin take a look at and after peripheral nerve damage. Intrathecal injection of C. Tex and C. Mil subfractions decreased flinching/licking conduct throughout the second part of formalin take a look at and attenuated thermal and mechanical allodynia in nerve damage mannequin. Therapy with proteolytic enzymes decreased CB1 internalization of subfractions, indicating the peptidergic nature of CB1 energetic element.

Q-PAK TEX (1/PK) - EACH

QPAK00TEX EACH
EUR 655.08

QUANTUM TEX CARTRIDGE (1/PK) - EACH

QTUM0TEX1SIG EACH
EUR 668.3

Recombinant Neisseria Gonorrhoeae tex Protein (aa 1-476)

VAng-Wyb2413-1mgEcoli 1 mg (E. coli)
EUR 6195.6
Description: Neisseria Gonorrhoeae Uncharacterized protein in region E, recombinant protein.

Recombinant Neisseria Gonorrhoeae tex Protein (aa 1-476)

VAng-Wyb2413-500gEcoli 500 µg (E. coli)
EUR 4426.8
Description: Neisseria Gonorrhoeae Uncharacterized protein in region E, recombinant protein.

Recombinant Neisseria Gonorrhoeae tex Protein (aa 1-476)

VAng-Wyb2413-50gEcoli 50 µg (E. coli)
EUR 3008.4
Description: Neisseria Gonorrhoeae Uncharacterized protein in region E, recombinant protein.

Tex101 (GFP-tagged) - Mouse testis expressed gene 101 (Tex101)

MG203183 10 µg Ask for price

Tex261 (GFP-tagged) - Mouse testis expressed gene 261 (Tex261)

MG201927 10 µg Ask for price

Tex101 (untagged) - Mouse testis expressed gene 101 (Tex101), (10ug)

MC205138 10 µg Ask for price

Tex261 (untagged) - Mouse testis expressed gene 261 (Tex261), (10ug)

MC207422 10 µg Ask for price

Tex101 (Myc-DDK-tagged) - Mouse testis expressed gene 101 (Tex101)

MR203183 10 µg Ask for price

Tex261 (Myc-DDK-tagged) - Mouse testis expressed gene 261 (Tex261)

MR201927 10 µg Ask for price

Tex19.1 (GFP-tagged) - Mouse testis expressed gene 19 (Tex19)

MG205325 10 µg Ask for price

Tex22 (GFP-tagged) - Mouse testis expressed gene 22 (Tex22)

MG201792 10 µg Ask for price

Tex12 (untagged) - Mouse testis expressed gene 12 (Tex12), (10ug)

MC205019 10 µg Ask for price

Tex22 (untagged) - Mouse testis expressed gene 22 (Tex22), (10ug)

MC205048 10 µg Ask for price

Tex16 (untagged) - Mouse testis expressed gene 16 (Tex16), (10ug)

MC223714 10 µg Ask for price

Tex15 (untagged) - Mouse testis expressed gene 15 (Tex15), (10ug)

MC225407 10 µg Ask for price

Tex19.2 (untagged) - Mouse testis expressed gene 19.2 (Tex19.2), (10ug)

MC211119 10 µg Ask for price

Tex10 (untagged) - Mouse testis expressed gene 10 (Tex10), (10ug)

MC222672 10 µg Ask for price

Tex13 (untagged) - Mouse testis expressed gene 13 (Tex13), (10ug)

MC211963 10 µg Ask for price

Tex24 (untagged) - Mouse testis expressed gene 24 (Tex24), (10ug)

MC215076 10 µg Ask for price

Tex37 (GFP-tagged) - Mouse RIKEN cDNA 1700011F03 gene (1700011F03Rik)

MG201605 10 µg Ask for price

Tex29 (GFP-tagged) - Mouse RIKEN cDNA 1700018L24 gene (1700018L24Rik)

MG201736 10 µg Ask for price

Tex2 (untagged) - Mouse testis expressed gene 2 (Tex2), (10ug)

MC223646 10 µg Ask for price

Tex9 (untagged) - Mouse testis expressed gene 9 (Tex9), (10ug)

MC209517 10 µg Ask for price

Tex37 (untagged) - Mouse RIKEN cDNA 1700011F03 gene (1700011F03Rik), (10ug)

MC205074 10 µg Ask for price

Tex40 (untagged) - Mouse RIKEN cDNA 1700019N12 gene (1700019N12Rik), (10ug)

MC210481 10 µg Ask for price

Tex35 (untagged) - Mouse RIKEN cDNA 1700057K13 gene (1700057K13Rik), (10ug)

MC211423 10 µg Ask for price

Tex36 (untagged) - Mouse RIKEN cDNA 4930404H21 gene (4930404H21Rik), (10ug)

MC211463 10 µg Ask for price

Tex38 (untagged) - Mouse RIKEN cDNA 4930544O15 gene (4930544O15Rik), (10ug)

MC211595 10 µg Ask for price

Tex29 (untagged) - Mouse RIKEN cDNA 1700018L24 gene (1700018L24Rik), (10ug)

MC211650 10 µg Ask for price

Tex30 (untagged) - Mouse RIKEN cDNA 1700029F09 gene (1700029F09Rik), (10ug)

MC211672 10 µg Ask for price

Tex26 (untagged) - Mouse RIKEN cDNA 4930588N13 gene (4930588N13Rik), (10ug)

MC211700 10 µg Ask for price

Tex16 (GFP-tagged) - Mouse testis expressed gene 16 (Tex16), (10ug)

MG212346 10 µg Ask for price

Tex13 (GFP-tagged) - Mouse testis expressed gene 13 (Tex13), (10ug)

MG213779 10 µg Ask for price

Tex10 (GFP-tagged) - Mouse testis expressed gene 10 (Tex10), (10ug)

MG220109 10 µg Ask for price

Tex14 (GFP-tagged) - Mouse testis expressed gene 14 (Tex14), (10ug)

MG220965 10 µg Ask for price

Tex24 (GFP-tagged) - Mouse testis expressed gene 24 (Tex24), (10ug)

MG215271 10 µg Ask for price

Tex15 (GFP-tagged) - Mouse testis expressed gene 15 (Tex15), (10ug)

MG215456 10 µg Ask for price

Tex19.2 (GFP-tagged) - Mouse testis expressed gene 19.2 (Tex19.2), (10ug)

MG222451 10 µg Ask for price

Tex12 (Myc-DDK-tagged) - Mouse testis expressed gene 12 (Tex12)

MR200619 10 µg Ask for price

Tex19.2 (Myc-DDK-tagged) - Mouse testis expressed gene 19.2 (Tex19.2)

MR222451 10 µg Ask for price

Tex10 (Myc-DDK-tagged) - Mouse testis expressed gene 10 (Tex10)

MR220109 10 µg Ask for price

Tex16 (Myc-DDK-tagged) - Mouse testis expressed gene 16 (Tex16)

MR212346 10 µg Ask for price

Tex22 (Myc-DDK-tagged) - Mouse testis expressed gene 22 (Tex22)

MR201792 10 µg Ask for price

Tex19.1 (Myc-DDK-tagged) - Mouse testis expressed gene 19.1 (Tex19.1)

MR205325 10 µg Ask for price

Tex24 (Myc-DDK-tagged) - Mouse testis expressed gene 24 (Tex24)

MR215271 10 µg Ask for price

Tex13 (Myc-DDK-tagged) - Mouse testis expressed gene 13 (Tex13)

MR213779 10 µg Ask for price

Tex15 (Myc-DDK-tagged) - Mouse testis expressed gene 15 (Tex15)

MR215456 10 µg Ask for price

Tex264 (untagged) - Mouse testis expressed gene 264 (Tex264), transcript variant 2

MC226937 10 µg Ask for price

Tex264 (untagged) - Mouse testis expressed gene 264 (Tex264), transcript variant 3

MC226938 10 µg Ask for price

Tex19.2 (untagged ORF) - Rat testis expressed gene 19.2 (Tex19.2), (10 ug)

RN202913 10 µg Ask for price

Tex21 (untagged ORF) - Rat testis expressed gene 21 (Tex21), (10 ug)

RN204010 10 µg Ask for price

Tex10 (untagged ORF) - Rat testis expressed gene 10 (Tex10), (10 ug)

RN213012 10 µg Ask for price

Tex19.1 (untagged ORF) - Rat testis expressed gene 19 (Tex19), (10 ug)

RN206124 10 µg Ask for price

Tex9 (GFP-tagged) - Mouse testis expressed gene 9 (Tex9), (10ug)

MG220617 10 µg Ask for price

Tex2 (GFP-tagged) - Mouse testis expressed gene 2 (Tex2), (10ug)

MG215727 10 µg Ask for price

Tex30 (GFP-tagged) - Mouse RIKEN cDNA 1700029F09 gene (1700029F09Rik), (10ug)

MG212434 10 µg Ask for price

Tex26 (GFP-tagged) - Mouse RIKEN cDNA 4930588N13 gene (4930588N13Rik), (10ug)

MG212748 10 µg Ask for price

Tex36 (GFP-tagged) - Mouse RIKEN cDNA 4930404H21 gene (4930404H21Rik), (10ug)

MG214201 10 µg Ask for price

Tex40 (GFP-tagged) - Mouse RIKEN cDNA 1700019N12 gene (1700019N12Rik), (10ug)

MG214418 10 µg Ask for price

Tex35 (GFP-tagged) - Mouse RIKEN cDNA 1700057K13 gene (1700057K13Rik), (10ug)

MG214667 10 µg Ask for price

Tex38 (GFP-tagged) - Mouse RIKEN cDNA 4930544O15 gene (4930544O15Rik), (10ug)

MG214997 10 µg Ask for price

Tex2 (Myc-DDK-tagged) - Mouse testis expressed gene 2 (Tex2)

MR215727 10 µg Ask for price

Tex9 (Myc-DDK-tagged) - Mouse testis expressed gene 9 (Tex9)

MR220617 10 µg Ask for price

Tex30 (Myc-DDK-tagged) - Mouse RIKEN cDNA 1700029F09 gene (1700029F09Rik)

MR212434 10 µg Ask for price

Tex26 (Myc-DDK-tagged) - Mouse RIKEN cDNA 4930588N13 gene (4930588N13Rik)

MR212748 10 µg Ask for price

Tex29 (Myc-DDK-tagged) - Mouse RIKEN cDNA 1700018L24 gene (1700018L24Rik)

MR201736 10 µg Ask for price

Tex37 (Myc-DDK-tagged) - Mouse RIKEN cDNA 1700011F03 gene (1700011F03Rik)

MR201605 10 µg Ask for price

Tex38 (Myc-DDK-tagged) - Mouse RIKEN cDNA 4930544O15 gene (4930544O15Rik)

MR214997 10 µg Ask for price

Tex36 (Myc-DDK-tagged) - Mouse RIKEN cDNA 4930404H21 gene (4930404H21Rik)

MR214201 10 µg Ask for price

Tex40 (Myc-DDK-tagged) - Mouse RIKEN cDNA 1700019N12 gene (1700019N12Rik)

MR214418 10 µg Ask for price

Tex35 (Myc-DDK-tagged) - Mouse RIKEN cDNA 1700057K13 gene (1700057K13Rik)

MR214667 10 µg Ask for price

Tex264 (untagged) - Mouse testis expressed gene 264 (Tex264), transcript variant 1, (10ug)

MC200096 10 µg Ask for price

Tex264 (GFP-tagged) - Mouse testis expressed gene 264 (Tex264), transcript variant 1

MG204389 10 µg Ask for price

Lenti ORF clone of Tex101 (mGFP-tagged) - Mouse testis expressed gene 101 (Tex101)

MR203183L4 10 µg Ask for price

Lenti ORF clone of Tex261 (mGFP-tagged) - Mouse testis expressed gene 261 (Tex261)

MR201927L4 10 µg Ask for price

Tex14 (untagged) - Mouse testis expressed gene 14 (Tex14), transcript variant 1

MC229597 10 µg Ask for price

Tex264 (Myc-DDK-tagged) - Mouse testis expressed gene 264 (Tex264), transcript variant 1

MR204389 10 µg Ask for price

Tex264 (myc-DDK-tagged) - Mouse testis expressed gene 264 (Tex264), transcript variant 2

MR229148 10 µg Ask for price

Tex264 (myc-DDK-tagged) - Mouse testis expressed gene 264 (Tex264), transcript variant 3

MR229149 10 µg Ask for price

Lenti ORF clone of Tex101 (Myc-DDK-tagged) - Mouse testis expressed gene 101 (Tex101)

MR203183L3 10 µg Ask for price

Lenti ORF clone of Tex261 (Myc-DDK-tagged) - Mouse testis expressed gene 261 (Tex261)

MR201927L3 10 µg Ask for price

Tex19.1 (Myc-DDK-tagged ORF) - Rat testis expressed gene 19 (Tex19), (10 ug)

RR206124 10 µg Ask for price

Tex19.2 (Myc-DDK-tagged ORF) - Rat testis expressed gene 19.2 (Tex19.2), (10 ug)

RR202913 10 µg Ask for price

Tex21 (Myc-DDK-tagged ORF) - Rat testis expressed gene 21 (Tex21), (10 ug)

RR204010 10 µg Ask for price

Tex10 (Myc-DDK-tagged ORF) - Rat testis expressed gene 10 (Tex10), (10 ug)

RR213012 10 µg Ask for price

Tex14 (untagged) - Mouse testis expressed gene 14 (Tex14), transcript variant 2, (10ug)

MC224488 10 µg Ask for price

Tex21 (untagged) - Mouse testis expressed gene 21 (Tex21), transcript variant 2, (10ug)

MC217489 10 µg Ask for price

Tex11 (untagged) - Mouse testis expressed gene 11 (Tex11), transcript variant 2, (10ug)

MC220865 10 µg Ask for price

Tex11 (untagged) - Mouse testis expressed gene 11 (Tex11), transcript variant 1, (10ug)

MC222795 10 µg Ask for price

Tex21 (untagged) - Mouse testis expressed gene 21 (Tex21), transcript variant 1, (10ug)

MC219206 10 µg Ask for price

Lenti ORF clone of Tex12 (mGFP-tagged) - Mouse testis expressed gene 12 (Tex12)

MR200619L4 10 µg Ask for price

Lenti ORF clone of Tex19.2 (mGFP-tagged) - Mouse testis expressed gene 19.2 (Tex19.2)

MR222451L4 10 µg Ask for price

Lenti ORF clone of Tex10 (mGFP-tagged) - Mouse testis expressed gene 10 (Tex10)

MR220109L4 10 µg Ask for price

Lenti ORF clone of Tex16 (mGFP-tagged) - Mouse testis expressed gene 16 (Tex16)

MR212346L4 10 µg Ask for price

Lenti ORF clone of Tex22 (mGFP-tagged) - Mouse testis expressed gene 22 (Tex22)

MR201792L4 10 µg Ask for price

Lenti ORF clone of Tex19.1 (mGFP-tagged) - Mouse testis expressed gene 19.1 (Tex19.1)

MR205325L4 10 µg Ask for price

Lenti ORF clone of Tex24 (mGFP-tagged) - Mouse testis expressed gene 24 (Tex24)

MR215271L4 10 µg Ask for price

Lenti ORF clone of Tex13 (mGFP-tagged) - Mouse testis expressed gene 13 (Tex13)

MR213779L4 10 µg Ask for price

Lenti ORF clone of Tex2 (mGFP-tagged) - Mouse testis expressed gene 2 (Tex2)

MR215727L4 10 µg Ask for price

Lenti ORF clone of Tex9 (mGFP-tagged) - Mouse testis expressed gene 9 (Tex9)

MR220617L2 10 µg Ask for price

Lenti ORF clone of Tex9 (mGFP-tagged) - Mouse testis expressed gene 9 (Tex9)

MR220617L4 10 µg Ask for price

Tex33 (untagged) - Mouse RIKEN cDNA 1700061J05 gene (1700061J05Rik), transcript variant 3, (10ug)

MC211415 10 µg Ask for price

Tex33 (untagged) - Mouse RIKEN cDNA 1700061J05 gene (1700061J05Rik), transcript variant 1, (10ug)

MC211416 10 µg Ask for price

Tex33 (untagged) - Mouse RIKEN cDNA 1700061J05 gene (1700061J05Rik), transcript variant 2, (10ug)

MC211417 10 µg Ask for price

Tex21 (GFP-tagged) - Mouse testis expressed gene 21 (Tex21) transcript variant 1, (10ug)

MG213792 10 µg Ask for price

Tex11 (GFP-tagged) - Mouse testis expressed gene 11 (Tex11) transcript variant 1, (10ug)

MG222179 10 µg Ask for price

Tex11 (GFP-tagged) - Mouse testis expressed gene 11 (Tex11) transcript variant 2, (10ug)

MG222182 10 µg Ask for price

Tex11 (Myc-DDK-tagged) - Mouse testis expressed gene 11 (Tex11), transcript variant 1

MR222179 10 µg Ask for price

Tex11 (Myc-DDK-tagged) - Mouse testis expressed gene 11 (Tex11), transcript variant 2

MR222182 10 µg Ask for price

Tex14 (Myc-DDK-tagged) - Mouse testis expressed gene 14 (Tex14), transcript variant 2

MR220965 10 µg Ask for price

Tex21 (GFP-tagged) - Mouse testis expressed gene 21 (Tex21) transcript variant 2, (10ug)

MG214480 10 µg Ask for price

Tex21 (Myc-DDK-tagged) - Mouse testis expressed gene 21 (Tex21), transcript variant 1

MR213792 10 µg Ask for price

Tex21 (Myc-DDK-tagged) - Mouse testis expressed gene 21 (Tex21), transcript variant 2

MR214480 10 µg Ask for price

Tex14 (myc-DDK-tagged) - Mouse testis expressed gene 14 (Tex14), transcript variant 1

MR231808 10 µg Ask for price

Lenti ORF clone of Tex30 (mGFP-tagged) - Mouse RIKEN cDNA 1700029F09 gene (1700029F09Rik)

MR212434L4 10 µg Ask for price

Lenti ORF clone of Tex26 (mGFP-tagged) - Mouse RIKEN cDNA 4930588N13 gene (4930588N13Rik)

MR212748L4 10 µg Ask for price

Lenti ORF clone of Tex29 (mGFP-tagged) - Mouse RIKEN cDNA 1700018L24 gene (1700018L24Rik)

MR201736L4 10 µg Ask for price

Lenti ORF clone of Tex37 (mGFP-tagged) - Mouse RIKEN cDNA 1700011F03 gene (1700011F03Rik)

MR201605L4 10 µg Ask for price

Lenti ORF clone of Tex38 (mGFP-tagged) - Mouse RIKEN cDNA 4930544O15 gene (4930544O15Rik)

MR214997L4 10 µg Ask for price

Lenti ORF clone of Tex36 (mGFP-tagged) - Mouse RIKEN cDNA 4930404H21 gene (4930404H21Rik)

MR214201L4 10 µg Ask for price

Lenti ORF clone of Tex40 (mGFP-tagged) - Mouse RIKEN cDNA 1700019N12 gene (1700019N12Rik)

MR214418L4 10 µg Ask for price

Lenti ORF clone of Tex35 (mGFP-tagged) - Mouse RIKEN cDNA 1700057K13 gene (1700057K13Rik)

MR214667L4 10 µg Ask for price

Lenti ORF clone of Tex12 (Myc-DDK-tagged) - Mouse testis expressed gene 12 (Tex12)

MR200619L3 10 µg Ask for price

Lenti ORF clone of Tex19.2 (Myc-DDK-tagged) - Mouse testis expressed gene 19.2 (Tex19.2)

MR222451L3 10 µg Ask for price

Lenti ORF clone of Tex10 (Myc-DDK-tagged) - Mouse testis expressed gene 10 (Tex10)

MR220109L3 10 µg Ask for price

Lenti ORF clone of Tex16 (Myc-DDK-tagged) - Mouse testis expressed gene 16 (Tex16)

MR212346L3 10 µg Ask for price

Lenti ORF clone of Tex22 (Myc-DDK-tagged) - Mouse testis expressed gene 22 (Tex22)

MR201792L3 10 µg Ask for price

Lenti ORF clone of Tex19.1 (Myc-DDK-tagged) - Mouse testis expressed gene 19.1 (Tex19.1)

MR205325L3 10 µg Ask for price

Lenti ORF clone of Tex24 (Myc-DDK-tagged) - Mouse testis expressed gene 24 (Tex24)

MR215271L3 10 µg Ask for price

Lenti ORF clone of Tex13 (Myc-DDK-tagged) - Mouse testis expressed gene 13 (Tex13)

MR213779L3 10 µg Ask for price

Lenti ORF particles, Tex101 (GFP-tagged) - Mouse testis expressed gene 101 (Tex101), 200ul, >10^7 TU/mL

MR203183L4V 200 µl Ask for price

Lenti ORF particles, Tex261 (GFP-tagged) - Mouse testis expressed gene 261 (Tex261), 200ul, >10^7 TU/mL

MR201927L4V 200 µl Ask for price

Lenti ORF clone of Tex264 (mGFP-tagged) - Mouse testis expressed gene 264 (Tex264), transcript variant 1

MR204389L4 10 µg Ask for price

Lenti ORF particles, Tex101 (Myc-DDK-tagged) - Mouse testis expressed gene 101 (Tex101), 200ul, >10^7 TU/mL

MR203183L3V 200 µl Ask for price

Lenti ORF particles, Tex261 (Myc-DDK-tagged) - Mouse testis expressed gene 261 (Tex261), 200ul, >10^7 TU/mL

MR201927L3V 200 µl Ask for price

Lenti ORF clone of Tex2 (Myc-DDK-tagged) - Mouse testis expressed gene 2 (Tex2)

MR215727L3 10 µg Ask for price

Lenti ORF clone of Tex9 (Myc-DDK-tagged) - Mouse testis expressed gene 9 (Tex9)

MR220617L1 10 µg Ask for price

Lenti ORF clone of Tex9 (Myc-DDK-tagged) - Mouse testis expressed gene 9 (Tex9)

MR220617L3 10 µg Ask for price

Lenti ORF clone of Tex19.1 (mGFP-tagged ORF) - Rat testis expressed gene 19 (Tex19), (10 ug)

RR206124L4 10 µg Ask for price

Lenti ORF clone of Tex19.2 (mGFP-tagged ORF) - Rat testis expressed gene 19.2 (Tex19.2), (10 ug)

RR202913L4 10 µg Ask for price

Lenti ORF clone of Tex21 (mGFP-tagged ORF) - Rat testis expressed gene 21 (Tex21), (10 ug)

RR204010L4 10 µg Ask for price

Lenti ORF clone of Tex10 (mGFP-tagged ORF) - Rat testis expressed gene 10 (Tex10), (10 ug)

RR213012L4 10 µg Ask for price

Tex33 (Myc-DDK-tagged) - Mouse RIKEN cDNA 1700061J05 gene (1700061J05Rik), transcript variant 1

MR215828 10 µg Ask for price

Tex33 (Myc-DDK-tagged) - Mouse RIKEN cDNA 1700061J05 gene (1700061J05Rik), transcript variant 3

MR215842 10 µg Ask for price

Tex33 (Myc-DDK-tagged) - Mouse RIKEN cDNA 1700061J05 gene (1700061J05Rik), transcript variant 2

MR218679 10 µg Ask for price

Tex33 (GFP-tagged) - Mouse RIKEN cDNA 1700061J05 gene (1700061J05Rik) transcript variant 2, (10ug)

MG218679 10 µg Ask for price

Tex33 (GFP-tagged) - Mouse RIKEN cDNA 1700061J05 gene (1700061J05Rik) transcript variant 1, (10ug)

MG215828 10 µg Ask for price

Tex33 (GFP-tagged) - Mouse RIKEN cDNA 1700061J05 gene (1700061J05Rik) transcript variant 3, (10ug)

MG215842 10 µg Ask for price

Lenti ORF clone of Tex30 (Myc-DDK-tagged) - Mouse RIKEN cDNA 1700029F09 gene (1700029F09Rik)

MR212434L3 10 µg Ask for price

Lenti ORF clone of Tex26 (Myc-DDK-tagged) - Mouse RIKEN cDNA 4930588N13 gene (4930588N13Rik)

MR212748L3 10 µg Ask for price

Lenti ORF clone of Tex29 (Myc-DDK-tagged) - Mouse RIKEN cDNA 1700018L24 gene (1700018L24Rik)

MR201736L3 10 µg Ask for price

Lenti ORF clone of Tex37 (Myc-DDK-tagged) - Mouse RIKEN cDNA 1700011F03 gene (1700011F03Rik)

MR201605L3 10 µg Ask for price

Lenti ORF clone of Tex38 (Myc-DDK-tagged) - Mouse RIKEN cDNA 4930544O15 gene (4930544O15Rik)

MR214997L3 10 µg Ask for price

Lenti ORF clone of Tex36 (Myc-DDK-tagged) - Mouse RIKEN cDNA 4930404H21 gene (4930404H21Rik)

MR214201L3 10 µg Ask for price

Lenti ORF clone of Tex40 (Myc-DDK-tagged) - Mouse RIKEN cDNA 1700019N12 gene (1700019N12Rik)

MR214418L3 10 µg Ask for price

Lenti ORF clone of Tex35 (Myc-DDK-tagged) - Mouse RIKEN cDNA 1700057K13 gene (1700057K13Rik)

MR214667L3 10 µg Ask for price

Lenti ORF clone of Tex264 (Myc-DDK-tagged) - Mouse testis expressed gene 264 (Tex264), transcript variant 1

MR204389L3 10 µg Ask for price

Lenti ORF clone of Tex19.1 (Myc-DDK-tagged ORF) - Rat testis expressed gene 19 (Tex19), (10 ug)

RR206124L3 10 µg Ask for price

Lenti ORF clone of Tex19.2 (Myc-DDK-tagged ORF) - Rat testis expressed gene 19.2 (Tex19.2), (10 ug)

RR202913L3 10 µg Ask for price

Lenti ORF clone of Tex21 (Myc-DDK-tagged ORF) - Rat testis expressed gene 21 (Tex21), (10 ug)

RR204010L3 10 µg Ask for price

Lenti ORF clone of Tex10 (Myc-DDK-tagged ORF) - Rat testis expressed gene 10 (Tex10), (10 ug)

RR213012L3 10 µg Ask for price

Lenti ORF particles, Tex12 (GFP-tagged) - Mouse testis expressed gene 12 (Tex12), 200ul, >10^7 TU/mL

MR200619L4V 200 µl Ask for price

Lenti ORF particles, Tex19.2 (GFP-tagged) - Mouse testis expressed gene 19.2 (Tex19.2), 200ul, >10^7 TU/mL

MR222451L4V 200 µl Ask for price

Lenti ORF particles, Tex10 (GFP-tagged) - Mouse testis expressed gene 10 (Tex10), 200ul, >10^7 TU/mL

MR220109L4V 200 µl Ask for price
Additional HPLC purification revealed two potent antinociceptive subfractions inside C. Tex with CB1 and attainable CB2 exercise, with gentle to no negative effects within the CB tetrad evaluation. CB conopeptides will be remoted from these energetic Conus venom-derived samples and additional developed as novel analgesic brokers for the remedy of power ache utilizing cell based mostly or gene remedy approaches.

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