Wogonin Strengthens the Therapeutic Effects of Mesenchymal Stem Cells in DSS-Induced Colitis via Promoting IL-10 Production

Wogonin Strengthens the Therapeutic Effects of Mesenchymal Stem Cells in DSS-Induced Colitis via Promoting IL-10 Production

Inflammatory bowel ailments (IBD) are prevalent and debilitating ailments; their scientific treatment is desperately unmet. Mesenchymal stem cells (MSCs) are pluripotent stem cells with a number of immunomodulatory results, that are attributed to their efficacy within the IBD rodent mannequin.
Optimization of MSC regimes in IBD is an important step for his or her additional scientific software. Wogonin is a flavonoid-like compound, which confirmed in depth immunomodulatory and adjuvant results. This analysis is aimed toward investigating whether or not and the way Wogonin boosted the therapeutic effectivity of MSCs on DSS-induced colitis.
Our outcomes confirmed that the MSC therapy with Wogonin considerably alleviated the intestinal irritation in IBD mice by elevated IL-10 expression. In vitro experiments, Wogonin clearly raised the IL-10 manufacturing and ROS ranges of MSCs in a dose-dependent method. In the meantime, western blot knowledge advised Wogonin improves the IL-10 manufacturing by inducing transcript issue HIF-1α expression by way of AKT/GSK3β sign pathway.
Lastly, the favorable results of Wogonin on MSCs have been confirmed by IL-10 blockade experiment in vivo. Collectively, our outcomes advised that Wogonin considerably elevated the IL-10 manufacturing and enhanced the therapeutic results of MSCs in DSS-induced colitis. This work advised Wogonin as a novel optimum technique for MSC scientific software.
 Wogonin Strengthens the Therapeutic Effects of Mesenchymal Stem Cells in DSS-Induced Colitis via Promoting IL-10 Production

SUMO conjugation susceptibility of Akt/protein kinase B impacts the expression of the pluripotency transcription issue Nanog in embryonic stem cells

Akt/PKB is a kinase concerned within the regulation of all kinds of cell processes. Its exercise is modulated by various post-translational modifications (PTMs). Significantly, conjugation of the small ubiquitin-related modifier (SUMO) to this kinase impacts on a number of mobile features, similar to proliferation and splicing. In embryonic stem (ES) cells, this kinase is vital for pluripotency upkeep.
Amongst different features, Akt is understood to advertise the expression of Nanog, a central pluripotency transcription issue (TF). Nonetheless, the relevance of this particular PTM of Akt has not been beforehand analyzed on this context. On this work, we examine the impact of Akt1 variants with differential SUMOylation susceptibility on the expression of Nanog.
Our outcomes exhibit that each, the Akt1 functionality of being modified by SUMO conjugation and a useful SUMO conjugase exercise are required to induce Nanog gene expression. Likewise, we discovered that the frequent oncogenic E17Okay Akt1 mutant affected Nanog expression in ES cells additionally in a SUMOylatability dependent method.
Curiously, this final result takes locations in ES cells however not in a non-pluripotent heterologous system, suggesting the presence of an important issue for this induction in ES cells. Remarkably, the 2 main candidate components to mediate this induction, GSK3-β and Tbx3, are non-essential gamers of this impact, suggesting a posh mechanism in all probability involving non-canonical pathways.
Moreover, we discovered that Akt1 subcellular distribution doesn’t depend upon its SUMOylatability, indicating that Akt localization has no affect on the impact on Nanog, and that apart from the membrane localization of E17Okay Akt mutant, SUMOylation can also be required for its hyperactivity.
Our outcomes spotlight the influence of SUMO conjugation within the operate of a kinase related for a plethora of mobile processes, together with the management of a key pluripotency TF.
 Wogonin Strengthens the Therapeutic Effects of Mesenchymal Stem Cells in DSS-Induced Colitis via Promoting IL-10 Production

Results of graphene on morphology, microstructure and transcriptomic profiling of Pinus tabuliformis Carr. roots

Graphene has proven nice potential for bettering progress of many vegetation, however its impact on woody vegetation stays basically unstudied. On this work, Pinus tabuliformis Carr. bare-rooted seedlings grown open air in pots have been irrigated with a graphene resolution over a focus vary of 0-50 mg/L for six months. Graphene was discovered to stimulate root progress, with a maximal impact at 25 mg/L.
We then investigated root microstructure and carried out transcript profiling of root supplies handled with Zero and 25 mg/L graphene. Graphene therapy resulted in plasma-wall separation and destruction of membrane integrity in root cells.
Greater than 50 thousand of differentially expressed genes (DEGs) have been obtained by RNA sequencing, amongst which 6477 may very well be annotated utilizing different plant databases. The GO enrichment evaluation and KEGG pathway evaluation of the annotated DEGs indicated that abiotic stress responses, which resemble salt stress, have been induced by graphene therapy in roots, whereas responses to biotic stimuli have been inhibited.
Quite a few metabolic processes and hormone sign transduction pathways have been altered by the therapy. The expansion promotion results of graphene could also be mediated by encouraging proline synthesis, and suppression of the expression of the auxin response gene SMALL AUXIN UP-REGULATED RNA 41 (SAUR41), PYL genes which encode ABA receptors, and GSK3 homologs.

3-hydroxyanthranic acid will increase the sensitivity of hepatocellular carcinoma to sorafenib by reducing tumor cell stemness

Sorafenib is the FDA-approved first-line goal drug for HCC sufferers. Nonetheless, sorafenib solely confers 3-5 months of survival profit with <30% of HCC sufferers. Thus, it’s essential to develop a sensitizer for hepatocellular carcinoma (HCC) to sorafenib.
Right here, we report that in consultant HCC cell strains (SMMC-7721 and PLC8024) which can be insensitive to sorafenib, 3-HAA (50 μM) considerably enhances cell sensitivity to sorafenib to an extent that would not be defined by additive results. In nude mice carrying HCC xenograft, tumor progress is inhibited by sorafenib (10 mg/kg/day) or 3-HAA (100 mg/kg/day) alone. When utilized in mixture, the therapy successfully prevents the xenograft from rising.
In a set of mechanistic experiments, we discover enhanced AKT activation and elevated proportion of CD44+CD133+ cells in sorafenib-resistant HCC cells and tissues. The proportion of CD44+CD133+ cells is decreased upon 3-HAA therapy in each cultured cells and mouse xenografts, suggesting that 3-HAA may lower the stemness of HCC. We additionally detect decreased phosphorylation of AKT, a regulator of the GSK3β/β-catenin signaling upon 3-HAA therapy.

Human Glycogen Synthase Kinase 3 Alpha (GSK3a) ELISA Kit

RDR-GSK3a-Hu-48Tests 48 Tests
EUR 500

Human Glycogen Synthase Kinase 3 Alpha (GSK3a) ELISA Kit

RDR-GSK3a-Hu-96Tests 96 Tests
EUR 692

Rat Glycogen Synthase Kinase 3 Alpha (GSK3a) ELISA Kit

RDR-GSK3a-Ra-48Tests 48 Tests
EUR 534

Rat Glycogen Synthase Kinase 3 Alpha (GSK3a) ELISA Kit

RDR-GSK3a-Ra-96Tests 96 Tests
EUR 742

Human Glycogen Synthase Kinase 3 Alpha (GSK3a) ELISA Kit

RD-GSK3a-Hu-48Tests 48 Tests
EUR 478

Human Glycogen Synthase Kinase 3 Alpha (GSK3a) ELISA Kit

RD-GSK3a-Hu-96Tests 96 Tests
EUR 662

Rat Glycogen Synthase Kinase 3 Alpha (GSK3a) ELISA Kit

RD-GSK3a-Ra-48Tests 48 Tests
EUR 511

Rat Glycogen Synthase Kinase 3 Alpha (GSK3a) ELISA Kit

RD-GSK3a-Ra-96Tests 96 Tests
EUR 709

HEK-293T Telomerase Over-Expressing Cell Pellet

abx069991-1Pellet 1 Pellet
EUR 398
  • Shipped within 1-3 working days.

Gsk3a/ Rat Gsk3a ELISA Kit

ELI-02619r 96 Tests
EUR 886

GSK3A antibody

20R-1287 100 ug
EUR 377
Description: Rabbit polyclonal GSK3A antibody

GSK3A antibody

70R-17614 50 ul
EUR 435
Description: Rabbit polyclonal GSK3A antibody

GSK3a antibody

70R-11868 100 ug
EUR 447
Description: Rabbit polyclonal GSK3a antibody

GSK3A Antibody

36917-100ul 100ul
EUR 252

GSK3A Antibody

43681-100ul 100ul
EUR 252

GSK3A Antibody

1-CSB-PA002836
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against GSK3A. Recognizes GSK3A from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IP, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IP:2-5ug/mglysate.ELISA:1/20000

GSK3A Antibody

1-CSB-PA05369A0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against GSK3A. Recognizes GSK3A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF; Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200

GSK3A Antibody

1-CSB-PA147596
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
  • Form: Liquid
  • Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Antigen affinity purification
Description: A polyclonal antibody against GSK3A. Recognizes GSK3A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:50-1:200

GSK3A Antibody

1-CSB-PA932427
  • EUR 317.00
  • EUR 244.00
  • 100ul
  • 50ul
  • Form: Liquid
  • Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Antigen affinity purification
Description: A polyclonal antibody against GSK3A. Recognizes GSK3A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:10000, IHC:1:50-1:200

GSK3A Antibody

CSB-PA205981-
EUR 335
  • Form: liquid
  • Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Antigen Affinity Purified
Description: A polyclonal antibody against GSK3A. Recognizes GSK3A from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

GSK3A Antibody

CSB-PA205981-100ul 100ul
EUR 314
  • Form: liquid
  • Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Antigen Affinity Purified
Description: A polyclonal antibody against GSK3A. Recognizes GSK3A from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

GSK3A Antibody

1-CSB-PA009962GA01HU
  • EUR 597.00
  • EUR 333.00
  • 150ul
  • 50ul
  • Form: Liquid
  • Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20℃, Avoid freeze / thaw cycles. Antigen Affinity Purified
Description: A polyclonal antibody against GSK3A. Recognizes GSK3A from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

GSK3A siRNA

20-abx902343
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol
  • Shipped within 5-10 working days.

GSK3A siRNA

20-abx918787
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol
  • Shipped within 5-10 working days.

GSK3A siRNA

20-abx918788
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol
  • Shipped within 5-10 working days.

Chymase reagent

30C-CP1129 5 units
EUR 2185
Description: Purified native Human Chymase reagent

Traut's Reagent

2330-1000
EUR 349

Traut's Reagent

2330-500
EUR 207

MTS Reagent

2808-1000
EUR 990

MTS Reagent

2808-250
EUR 365

MTT Reagent

2809-1G
EUR 180

MTT Reagent

2809-5G
EUR 544

BOP reagent

5-02141 25g Ask for price

BOP reagent

5-02142 100g Ask for price

Bluing Reagent

BRT030 30 ml
EUR 60

Bluing Reagent

BRT125 125 ml
EUR 63

Bluing Reagent

BRT3800 1 Gal.
EUR 184

Bluing Reagent

BRT500 500 ml
EUR 76

Bluing Reagent

BRT999 1000 ml
EUR 88

BOP reagent

A7015-100000 100 g
EUR 200
Description: A peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.

BOP reagent

A7015-25000 25 g
EUR 113
Description: A peptide coupling reagent. Can be used in the preparation of phenyl esters of amino acids which have been shown to be valuable as blocked derivatives of amino acids in the field of peptide synthesis.

Beaucage reagent

HY-100951 10mM/1mL
EUR 126

Bradford reagent

BDE641 100ml
EUR 61.01
  • Product category: Biochemicals/Biology Reagents/Protein Related

Arabidopsis Thaliana Lysate

30R-AA023 150 ug
EUR 156
Description: Arabidopsis Thaliana Plant Lysate

CMV Cell Lysate

35-1867 1 mg
EUR 1835
Description: CMV enriched cell lysate

HSV1 Cell Lysate

35-1872 1 ml
EUR 394
Description: HSV1 enriched cell lysate

HSV2 Cell Lysate

35-1873 1 ml
EUR 394
Description: HSV2 enriched cell lysate

JM109-lysate Antibody

abx234439-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

BL21-lysate Antibody

abx230905-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

DH5a-lysate Antibody

abx232362-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Green Algae Lysate

PABL-1306 50 ug
EUR 164

GSK3A Rabbit pAb

A0645-100ul 100 ul
EUR 308

GSK3A Rabbit pAb

A0645-200ul 200 ul
EUR 459

GSK3A Rabbit pAb

A0645-20ul 20 ul
EUR 183

GSK3A Rabbit pAb

A0645-50ul 50 ul
EUR 223

GSK3A Blocking Peptide

33R-6426 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of GSK3A antibody, catalog no. 20R-1287

GSK3A/GSK3B Antibody

1-CSB-PA002838
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against GSK3A/GSK3B. Recognizes GSK3A/GSK3B from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

GSK3A/B Antibody

DF6806 200ul
EUR 304
Description: GSK3A/B Antibody detects endogenous levels of total GSK3A/B.

GSK3A (pS21) Antibody

20-abx123381
  • EUR 495.00
  • EUR 704.00
  • EUR 217.00
  • EUR 356.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

GSK3A Conjugated Antibody

C43681 100ul
EUR 397

GSK3A Conjugated Antibody

C36917 100ul
EUR 397

GSK3A / GSK3B Antibody

20-abx328487
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

GSK3A (pS21) Antibody

20-abx000172
  • EUR 495.00
  • EUR 704.00
  • EUR 356.00
  • 100 ul
  • 200 ul
  • 50 ul
  • Shipped within 5-10 working days.

anti- GSK3A antibody

FNab03672 100µg
EUR 505.25
  • Recommended dilution: WB: 1:500 - 1:2000
  • IHC: 1:50 - 1:200
  • Immunogen: glycogen synthase kinase 3 alpha
  • Uniprot ID: P49840
  • Gene ID: 2931
  • Research Area: Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience,
  • Show more
Description: Antibody raised against GSK3A

anti- GSK3A antibody

FNab10243 100µg
EUR 505.25
  • Recommended dilution: WB: 1:500 - 1:2000
  • Immunogen: glycogen synthase kinase 3 alpha
  • Uniprot ID: P49840
  • Gene ID: 2931
  • Research Area: Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience, Cell Division and P
  • Show more
Description: Antibody raised against GSK3A

Anti-GSK3A antibody

PAab03672 100 ug
EUR 355

Anti-GSK3A antibody

STJ23877 100 µl
EUR 277
Description: This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease.

BSA (Reagent Grade)

30-AB79 1 kg
EUR 1552
Description: Reagent Grade Bovine Serum Albumin (99% pure)

BSA (Reagent Grade)

30-AB81 200 grams
EUR 476
Description: Reagent Grade Sulphydryl Blocked BSA (99% pure)

Griess Reagent Kit

30100 1KIT
EUR 149
Description: Minimum order quantity: 1 unit of 1KIT

BODIPY-Acetylene Reagent

2594-1
EUR 207

BODIPY-Acetylene Reagent

2594-5
EUR 675

Biotin reagent (HRP)

65C-CE0202 5 mg
EUR 244
Description: HRP conjugated biotin labelling reagent

Convoy? Transfection Reagent

1110-1ml
EUR 341

Bradford Dye Reagent

0209R 100 ml
EUR 131

HAMA blocking reagent

85R-1001 1 gram
EUR 1974
Description: HAMA Blocking Reagent for use in immunoassays such as ELISA

HAMA blocking reagent

85R-1001P 1 gram
EUR 2190
Description: HAMA Blocking Reagent for use in immunoassays such as ELISA

HAMA blocking reagent

85R-1003 1 gram
EUR 1974
Description: HAMA Blocking Reagent for use in immunoassays such as Rapid Tests

HAMA blocking reagent

85R-1014 50 mg
EUR 192
Description: HAMA blocking reagent for use in assays specific for clinical false positive samples

HAMA blocking reagent

85R-1025 50 mg
EUR 192
Description: HAMA blocking reagent for use in immunoassays

HAMA blocking reagent

85R-1026 50 mg
EUR 192
Description: HAMA blocking reagent for use in immunoassays

Girard's reagent T

20-abx184099
  • EUR 203.00
  • EUR 314.00
  • 100 g
  • 500 g
  • Shipped within 1-2 weeks.

EL Transfection Reagent

20-abx098880
  • EUR 384.00
  • EUR 537.00
  • 0.75 ml
  • 1.5 ml
  • Shipped within 5-10 working days.

Mycoplasma Prevention Reagent

20-abx098886
  • EUR 425.00
  • EUR 509.00
  • 1 ml
  • 5 ml
  • Shipped within 5-10 working days.

Alcohol, Reagent (70%)

EAS500 500 ml
EUR 79

Alcohol, Reagent (70%)

EAS999 1000 ml
EUR 101

BCA Reagent, 16ML

C144-16ML 16ML
EUR 163

Biolipidure-1002-Reagent

Biolipidure-1002-10 10mL
EUR 196
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-1002-Reagent is a synthetic amphoteric polymer that can be substituted for BSA in tubidimetric immunoassays. Biolipidure-1002 is an excellent blocker and also enhances assay sensitivity. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1002-Reagent

Biolipidure-1002-100 100mL
EUR 1223
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-1002-Reagent is a synthetic amphoteric polymer that can be substituted for BSA in tubidimetric immunoassays. Biolipidure-1002 is an excellent blocker and also enhances assay sensitivity. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-103-Reagent

Biolipidure-103-10 10mL
EUR 196
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-103-Reagent is a synthetic amphoteric polymer that can be substituted for BSA. It has been shown to enhance signals in rapid tests, western blots, and other similar immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-103-Reagent

Biolipidure-103-100 100mL
EUR 1223
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-103-Reagent is a synthetic amphoteric polymer that can be substituted for BSA. It has been shown to enhance signals in rapid tests, western blots, and other similar immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1201-Reagent

Biolipidure-1201-10 10mL
EUR 196
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-1201 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1201-Reagent

Biolipidure-1201-100 100mL
EUR 1223
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-1201 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1301-Reagent

Biolipidure-1301-10 10mL
EUR 196
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-1301 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-1301-Reagent

Biolipidure-1301-100 100mL
EUR 1223
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-1301 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-203-Reagent

Biolipidure-203-10 10mL
EUR 196
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-203 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-203 has been shown to enhance signal strength by improving signal-to-noise in ELISAs, EIAs, and related immunoassays. It also functions as an effective blocker and stabilizer in these assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-203-Reagent

Biolipidure-203-100 100mL
EUR 1223
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-203 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-203 has been shown to enhance signal strength by improving signal-to-noise in ELISAs, EIAs, and related immunoassays. It also functions as an effective blocker and stabilizer in these assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-206-Reagent

Biolipidure-206-10 10mL
EUR 196
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-206 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-206 enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-206-Reagent

Biolipidure-206-100 100mL
EUR 1223
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-206 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-206 enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-405-Reagent

Biolipidure-405-10 10mL
EUR 196
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-405 Reagent is a synthetic anionic polymer that can be used to enhance immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-405-Reagent

Biolipidure-405-100 100mL
EUR 1223
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-405 Reagent is a synthetic anionic polymer that can be used to enhance immunochromatographic assays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-502-Reagent

Biolipidure-502-10 10mL
EUR 196
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-502 Reagent is a synthetic cationic polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-502-Reagent

Biolipidure-502-100 100mL
EUR 1223
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-502 Reagent is a synthetic cationic polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-702-Reagent

Biolipidure-702-10 10mL
EUR 196
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-702 Reagent is a synthetic amphoteric polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-702-Reagent

Biolipidure-702-100 100mL
EUR 1223
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-702 Reagent is a synthetic amphoteric polymer. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-802-Reagent

Biolipidure-802-10 10mL
EUR 196
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-802 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-802 generally enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, Rapid-test, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

Biolipidure-802-Reagent

Biolipidure-802-100 100mL
EUR 1223
  • Biolipidure enhances sensitivity and accuracy.
  • Biolipidure suppresses non-specific adsorption.
  • Biolipidure stabilizes antibodies and enzymes.
  • Biolipidure eliminates lot-to-lot variations.
  • Biolipidure does not require biohazardous handling.
Description: The Biolipidure-802 Reagent is a synthetic amphoteric polymer that can be substituted for BSA. Biolipidure-802 generally enhances signal strength, functions as an effective blocker, and stabilizes proteins and antibodies in ELISAs, EIAs, Rapid-test, and related immunoassays. Applications include: Immunoassays, Western blots, Immunohistochemistry, Turbidimetric assays, Immunochromatography, and Bead based assays. Benefits include: No lot to lot variation, No animal derived materials, Non-specific adsorption suppression, Stabilization of immobilized antibody, Stabilization of enzyme-antibody conjugate, Enzyme-substrate reaction enhancement and aggregation reaction enhancement

FcR blocking Reagent

20-abx290024
  • EUR 377.00
  • EUR 516.00
  • 200 tests
  • 400 tests
  • Shipped within 2-3 weeks.

Detection Reagent A

abx296004-120ul 120 ul
EUR 321
  • Shipped within 5-10 working days.

Mycoplasma Prevention Reagent

20-abx298005
  • EUR 203.00
  • EUR 286.00
  • 1 ml
  • 5 ml
  • Shipped within 5-10 working days.

PhosphoBlocker Blocking Reagent

AKR-103 1L
EUR 328
Description: Most commercially available Western blot blockers, such as dry milk or serum, are sufficient to block unreactive sites on the membrane. However, they are not designed to preserve phosphoprotein antigens during blotting. Our PhosphoBLOCKER Blocking Reagent provides superior blocking by maximizing signal-to-noise ratio. The PhosphoBLOCKER reagent particluarly excels with very low levels of endogenous phopsphoproteins.

PhosphoBlocker Blocking Reagent

AKR-104 4L
EUR 711
Description: Most commercially available Western blot blockers, such as dry milk or serum, are sufficient to block unreactive sites on the membrane. However, they are not designed to preserve phosphoprotein antigens during blotting. Our PhosphoBLOCKER Blocking Reagent provides superior blocking by maximizing signal-to-noise ratio. The PhosphoBLOCKER reagent particluarly excels with very low levels of endogenous phopsphoproteins.

Tri-RNA Reagent

FATRR-001 100ml
EUR 236

Tri-RNA Reagent

FATRR-002 50ml
EUR 176

Tri-RNA Reagent

FATRR-003 450ml
EUR 645

LP4K Transfection Reagent

LP4K 1.0 ml / vial
EUR 304
Description: Lipid based transfection reagent for large plasmid and multiple plasmid transfection in both adhesive and suspenstion cell types.

PureFection Transfection Reagent

LV750A-1 1 ml
EUR 359
  • Category: Lentiviral Technology

HighGene transfection reagent

RM09014 1000μl
EUR 270

TissueDigest Reagent, 20X

T101 10ml
EUR 210

ExFect2000 Transfection Reagent

T202-01 0.5 ml
EUR 227

ExFect2000 Transfection Reagent

T202-02 1 ml
EUR 316

ExFect2000 Transfection Reagent

T202-03 5 ml
EUR 1052

Dissociation Reagent, 1ML

X017-1ML 1ML
EUR 109

Dissociation Reagent, 25ML

X017-25ML 25ML
EUR 258

Dissociation Reagent, 5ML

X017-5ML 5ML
EUR 122

Dissociation Reagent, 1ML

X058-1ML 1ML
EUR 73

Dissociation Reagent, 5ML

X058-5ML 5ML
EUR 109

DTT (Cleland's reagent)

DB0058 5g
EUR 84.8
  • Product category: Electrophoresis Related/Reducing Agents

DTNB (Ellman's Reagent)

DB0113 5g
EUR 97.85
  • Product category: Biochemicals/Indicators/Stains/Peptide/Protein Related

Ethyl acetate Reagent

EC4600 1L
EUR 79
  • Product category: Biochemicals/Solvents

n-Heptane Reagent

HC5400 1L
EUR 79
  • Product category: Biochemicals/Solvents

Human Brain Tissue Lysate

30R-AB017 150 ug
EUR 273
Description: Fresh tissue lysate isolated from human brain

Chicken Liver Tissue Lysate

30R-AC011 150 ug
EUR 192
Description: Freshly prepared tissue lysate isolated from liver of normal chicken

Human Cerebellum Tissue Lysate

30R-AC058 150 ug
EUR 290
Description: Freshly prepared tissue lysate isolated from cerebellum of human brain

Human Hippocampus Tissue Lysate

30R-AH 150 ug
EUR 273
Description: Isolated Human Hippocampus Tissue Lysate

Human Heart Tissue Lysate

30R-AH049 150 ug
EUR 534
Description: Fresh tissue lysate isolated from human heart

Jurkat cell Lysate (untreated)

2401-100
EUR 185

Human Kidney Tissue Lysate

30R-AK003 150 ug
EUR 219
Description: Fresh tissue lysate isolated from human kidney

Rabbit Liver Tissue Lysate

30R-AL003 150 ug
EUR 252
Description: Fresh tissue lysate prepared from rabbit liver

Human Lung Tissue Lysate

30R-AL006 150 ug
EUR 219
Description: Fresh tissue lysate isolated from human lung

Human Midbrain Tissue Lysate

30R-AM011 150 ug
EUR 257
Description: Fresh tissue lysate isolated from the midbrain of human brain

Human Pancreas Tissue Lysate

30R-AP030 150 ug
EUR 219
Description: Fresh tissue lysate isolated from human pancreas

Human Prostate Tissue Lysate

30R-AP031 150 ug
EUR 219
Description: Fresh tissue lysate prepared from normal human prostate

Human Pons Tissue Lysate

30R-AP033 150 ug
EUR 235
Description: Fresh tissue lysate isolated from the pons of human brain

Human Posterior Cortex Lysate

30R-AP034 150 ug
EUR 235
Description: Fresh tissue lysate isolated from the posterior cortex of human brain

Rat Retina Tissue Lysate

30R-AR005 150 ug
EUR 267
Description: Fresh tissue lysate prepared from the retina of rat eye

Human Striatum Tissue Lysate

30R-AS030 150 ug
EUR 327
Description: Fresh tissue lysate isolated from the striatum of human brain

Human Stomach Tissue Lysate

30R-AS039 150 ug
EUR 219
Description: Fresh tissue lysate isolated from human stomach

Human Thalamus Tissue Lysate

30R-AT053 150 ug
EUR 235
Description: Fresh tissue lysate isolated from the thalamus of human brain

JNK Activated Cell Lysate

7032-1
EUR 316

Akt Activated Cell Lysate

7036-1
EUR 316

BL21(DE3)-lysate Antibody

abx230903-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

BL21(plysS) -lysate Antibody

abx230904-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Human Lung Tumor lysate

HTL-1321 1 mg
EUR 773

Human Brain Tumor lysate

HTL-1322 1 mg
EUR 773

Human Breast Tumor lysate

HTL-1323 1 mg
EUR 773

Human Kidney Tumor lysate

HTL-1324 1 mg
EUR 773

Human Bladder Tumor lysate

HTL-1325 1 mg
EUR 773

Human Cervix Tumor lysate

HTL-1326 100ug
EUR 286

Human Duodenum Tumor lysate

HTL-1328 1 mg
EUR 895

Human Esophagus tumor lysate

HTL-1329 1 mg
EUR 773

Human Liver Tumor lysate

HTL-1330 1 mg
EUR 773

Human Lymphoma Tumor lysate

HTL-1331 1 mg
EUR 773

Human Ovary Tumor lysate

HTL-1333 1 mg
EUR 773

Human Pancreas Tumor lysate

HTL-1334 1 mg
EUR 773

Human Prostate Tumor lysate

HTL-1335 1 mg
EUR 773

Human Rectum Tumor lysate

HTL-1336 1 mg
EUR 773

Human Skin Tumor lysate

HTL-1337 1 mg
EUR 773

Human Spleen Tumor lysate

HTL-1339 1 mg
EUR 773

Human Stomach Tumor lysate

HTL-1340 1 mg
EUR 773

Human Testis Tumor lysate

HTL-1381 1 mg
EUR 773

Human Thymoma Tumor lysate

HTL-1382 1 mg
EUR 773

Human Thyroid Tumor lysate

HTL-1383 1 mg
EUR 773

Human Uterus Tumor lysate

HTL-1384 1 mg
EUR 773

CHO Lysate Antigen Concentrate

F018H 200 ul
EUR 604
  • Product category: Quality control/standard for molecular biology applications
Description: CHO Lysate Antigen Concentrate by Cygnus Technologies is available in Europe via Gentaur.

CHO Lysate Antigen Concentrate

F018R 1 ml
EUR 6225
  • Product category: Quality control/standard for molecular biology applications
Description: CHO Lysate Antigen Concentrate by Cygnus Technologies is available in Europe via Gentaur.

anti- JM109-lysate antibody

FNab04439 100µg
EUR 585
  • Immunogen: JM109-lysate
Description: Antibody raised against JM109-lysate
The AKT activator SC79 prompts GSK3 β/β-catenin signaling whereas the Wnt inhibitor XAV-939 abolishes 3-HAA inhibition of HCC progress in vitro and in mice. The present examine demonstrates that 3-HAA sensitizes HCC cells to sorafenib by lowering tumor stemness, suggesting it’s a promising molecule for HCC remedy.

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