Ae1 Ae3 Antibody Bafilomycin A1 Bile Acid Assay Bioassay Blog cDNA Ch 223191 Ldn 193189 Mmp Activity Assay Mothers Against Decapentaplegic Mouse Albumin Elisa Pamabrom 100Mg Ru 58841 Soft Agar Sr 9011 Trypsin Activity Assay Tubastatin A Valproic Acid Sodium Salt Western Blot
The novel AKT inhibitor Afuresertib suppresses human Merkel cell carcinoma MKL-1 cell growth
Merkel cell carcinoma (MCC) is a extremely aggressive neuroendocrine neoplasm of the pores and skin that’s related to exceedingly poor prognosis. The AKT/mTOR signaling pathway, which performs a pivotal function within the modulation of protein synthesis and cell survival, has been proven to be extremely necessary for Merkel cell carcinogenesis.
Within the present examine, our information point out that AKT has necessary regulatory capabilities in MCC cells and that inhibition of AKT with the novel ATP-competitive AKT inhibitor, Afuresertib, has widespread results on proliferative pathways.
Specifically, we show that remedy of MCC cells with Afuresertib led to the de-activation of mTOR and GSK3 pathway proteins whereas growing the activation of pro-apoptotic pathways via the upregulation of p16 expression and phospho-modulation of the Bcl-2-associated dying promoter. Total, Afuresertib remedy led to vital and strong inhibition of MCC cell proliferation, thus elevating intriguing questions relating to the potential efficacy of AKT inhibition for the longer term medical administration of MCCs.
An modern NRF2 nano-modulator induces lung most cancers ferroptosis and elicits an immunostimulatory tumor microenvironment
Simultaneous concentrating on of each the tumor microenvironment and most cancers cells by a single nanomedicine has not been reported up to now. Right here, we report the twin properties of zero-valent-iron nanoparticle (ZVI-NP) to induce cancer-specific cytotoxicity and anti-cancer immunity. Strategies: Most cancers-specific cytotoxicity induced by ZVI-NP was decided by MTT assay.
Mitochondria purposeful assay, immunofluorescence staining, Western blot, RT-qPCR, and ChIP-qPCR assays have been used to dissect the mechanism underlying ZVI-NP-induced ferroptotic most cancers cell dying. The therapeutic potential of ZVI-NP was evaluated in immunocompetent mice and humanized mice. Immune cell profiles of allografts and ex vivo cultured immune cells have been examined by stream cytometry evaluation, RT-qPCR assay, and immunofluorescence.
Outcomes: ZVI-NP triggered mitochondria dysfunction, intracellular oxidative stress, and lipid peroxidation, resulting in ferroptotic dying of lung most cancers cells. Degradation of NRF2 by GSK3/β-TrCP via AMPK/mTOR activation was enhanced in such cancer-specific ferroptosis. As well as, ZVI-NP attenuated self-renewal skill of most cancers and downregulated angiogenesis-related genes.
Importantly, ZVI-NP augmented anti-tumor immunity by shifting pro-tumor M2 macrophages to anti-tumor M1, lowering the inhabitants of regulatory T cells, downregulating PD-1 and CTLA4 in CD8+ T cells to potentiate their cytolytic exercise towards most cancers cells, whereas attenuating PD-L1 expression in most cancers cells in vitro and in tumor-bearing immunocompetent mice.
Specifically, ZVI-NPs preferentially accrued in tumor and lung tissues, resulting in outstanding suppression of tumor development and metastasis. Conclusions: This dual-functional nanomedicine established an efficient technique to synergistically induce ferroptotic most cancers cell dying and reprogram the immunosuppressive microenvironment, which highlights the potential of ZVI-NP as a complicated built-in anti-cancer technique.
Activation of Galanin Receptor 1 with M617 Attenuates Neuronal Apoptosis by way of ERK/GSK-3β/TIP60 Pathway After Subarachnoid Hemorrhage in Rats
Subarachnoid hemorrhage (SAH) is a devastating cerebrovascular illness. Neuronal apoptosis performs an necessary pathological function in early mind harm after SAH. Galanin receptor 1 (GalR1) activation was not too long ago proven to be anti-apoptotic within the setting of ischemic stroke.
This examine aimed to discover the anti-neuronal apoptosis impact of GalR1 activation after SAH, in addition to the underlying mechanisms. GalR1 CRISPR and GalR1 selective agonist, M617, was administered, respectively. Extracellular-signal-regulated kinase (ERK) inhibitor (U0126) and glycogen synthase kinase 3-beta (GSK3-β) CRISPR have been administered to analyze the involvement of the ERK/GSK3-β pathway in GalR1-mediated neuroprotection after SAH.
Consequence assessments included neurobehavioral checks, western blot, and immunohistochemistry. The outcomes confirmed that endogenous ligand galanin (Gal) and GalR1 have been markedly elevated within the ipsilateral mind hemisphere at 12 h and 24 h after SAH. GalR1 have been expressed primarily in neurons, however expression was additionally noticed in some astrocytes and microglia.
GalR1 CRISPR knockdown exacerbated neurological deficits and neuronal apoptosis 24 h after SAH. Furthermore, activation of GalR1 with M617 considerably improved short- and long-term neurological deficits however decreased neuronal apoptosis after SAH.
Moreover, GalR1 activation dysregulated the protein ranges of phosphorylated ERK and GSK-3β, however downregulated the phosphorylated Tat-interactive protein 60 (TIP60) and cleaved caspase-Three at 24 h after SAH. GalR1 CRISPR, U0126, and GSK-3β CRISPR abolished the helpful results of GalR1 activation at 24 h after SAH in rats. Collectively, the current examine demonstrated that activation of GalR1 utilizing M617 attenuated neuronal apoptosis via the ERK/GSK-3β/TIP60 pathway after SAH in rats. GalR1 might function a promising therapeutic goal for SAH sufferers.
Technology and characterization of iPSC-derived renal proximal tubule-like cells with prolonged stability
The renal proximal tubule is chargeable for re-absorption of nearly all of the glomerular filtrate and its correct operate is critical for whole-body homeostasis. Getting old, sure ailments and chemical-induced toxicity are elements that contribute to proximal tubule harm and power kidney illness development.
To higher perceive these processes, it might be advantageous to generate renal tissues from human induced pluripotent stem cells (iPSC). Right here, we report the differentiation and characterization of iPSC strains into proximal tubular-like cells (PTL).
The protocol is a step sensible publicity of small molecules and development elements, together with the GSK3 inhibitor (CHIR99021), the retinoic acid receptor activator (TTNPB), FGF9 and EGF, to drive iPSC to PTL by way of cell levels representing traits of early levels of renal improvement.
Genome-wide RNA sequencing confirmed that PTL clustered inside a kidney phenotype. PTL expressed proximal tubular-specific markers, together with megalin (LRP2), confirmed a polarized phenotype, and have been conscious of parathyroid hormone.
PTL might take up albumin and exhibited ABCB1 transport exercise. The phenotype was secure for as much as 7 days and was maintained after passaging. This protocol will kind the idea of an optimized technique for molecular investigations utilizing iPSC derived PTL.
When Good Kinases Go Rogue: GSK3, p38 MAPK and CDKs as Therapeutic Targets for Alzheimer’s and Huntington’s Illness
Alzheimer’s illness (AD) is a principally sporadic mind dysfunction characterised by cognitive decline ensuing from selective neurodegeneration within the hippocampus and cerebral cortex whereas Huntington’s illness (HD) is a monogenic inherited dysfunction characterised by motor abnormalities and psychiatric disturbances ensuing from selective neurodegeneration within the striatum. Though there have been quite a few medical trials for these ailments, they’ve been unsuccessful.
Analysis carried out over the previous three a long time by numerous laboratories has demonstrated that irregular actions of widespread kinases play a key function within the pathogenesis of each AD and HD in addition to a number of different neurodegenerative ailments. Distinguished amongst these kinases are glycogen synthase kinase (GSK3), p38 mitogen-activated protein kinase (MAPK) and a number of the cyclin-dependent kinases (CDKs).
After a short abstract of the molecular and cell biology of AD and HD this overview covers what is understood concerning the function of those three teams of kinases within the mind and within the pathogenesis of the 2 neurodegenerative issues.
 Rat Glycogen Synthase Kinase 3 Beta ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta ELISA Kit |
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 Rat Glycogen synthase kinase-3 beta ELISA Kit |
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Rat Glycogen synthase kinase-3 beta ELISA Kit |
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Rat Glycogen synthase kinase-3 beta ELISA Kit |
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Rat Glycogen synthase kinase-3 beta ELISA Kit |
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) Rat Glycogen Synthase Kinase 3 Beta ELISA Kit (GSK3b) |
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 ELISA Kit) Rat GSK3b (Glycogen Synthase Kinase 3 Beta) ELISA Kit |
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Rat GSK3b (Glycogen Synthase Kinase 3 Beta) ELISA Kit |
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Rat GSK3b (Glycogen Synthase Kinase 3 Beta) ELISA Kit |
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Rat GSK3b (Glycogen Synthase Kinase 3 Beta) ELISA Kit |
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 Rat Gsk3b/ Glycogen synthase kinase-3 beta ELISA Kit |
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Description: 2.7.11.1,Factor A,Serine/threonine-protein kinase GSK3B,FA |
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 ELISA Kit) Rat GSK3β(Glycogen synthase kinase-3 beta) ELISA Kit |
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Rat GSK3β(Glycogen synthase kinase-3 beta) ELISA Kit |
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Rat GSK3β(Glycogen synthase kinase-3 beta) ELISA Kit |
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Rat GSK3β(Glycogen synthase kinase-3 beta) ELISA Kit |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 0.094 ng/ml |
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 ELISA Kit for Rat Glycogen synthase kinase-3 beta |
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 ELISA Kit) Rat Glycogen Synthase Kinase 3 Beta (GSK3B) ELISA Kit |
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 ELISA Kit) Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Description: tissue homogenates, cell lysates or other biological fluids. |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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| DLR-GSK3b-Ra-48T | DL Develop | 48T | EUR 658.8 |
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Description: A sandwich quantitative ELISA assay kit for detection of Rat Glycogen Synthase Kinase 3 Beta (GSK3b) in samples from tissue homogenates, cell lysates or other biological fluids. |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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| DLR-GSK3b-Ra-96T | DL Develop | 96T | EUR 861.6 |
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Description: A sandwich quantitative ELISA assay kit for detection of Rat Glycogen Synthase Kinase 3 Beta (GSK3b) in samples from tissue homogenates, cell lysates or other biological fluids. |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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| DL-GSK3b-Ra | DL Develop | 96T | EUR 475 |
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Description: tissue homogenates, cell lysates or other biological fluids. |
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 ELISA Kit) Rat Glycogen Synthase Kinase 3 beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Description: sandwich |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Description: sandwich |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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| SED317Ra-10x96wellstestplate | Cloud-Clone | 10x96-wells test plate | EUR 6149.04 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Glycogen Synthase Kinase 3 Beta (GSK3b) in tissue homogenates, cell lysates and other biological fluids. |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Glycogen Synthase Kinase 3 Beta (GSK3b) in tissue homogenates, cell lysates and other biological fluids. |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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| SED317Ra-1x96wellstestplate | Cloud-Clone | 1x96-wells test plate | EUR 822.24 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Glycogen Synthase Kinase 3 Beta (GSK3b) in tissue homogenates, cell lysates and other biological fluids. |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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| SED317Ra-5x96wellstestplate | Cloud-Clone | 5x96-wells test plate | EUR 3340.08 |
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Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Glycogen Synthase Kinase 3 Beta (GSK3b) in tissue homogenates, cell lysates and other biological fluids. |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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| 4-SED317Ra | Cloud-Clone |
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Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Glycogen Synthase Kinase 3 Beta (GSK3b) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species. |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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| RD-GSK3b-Ra-48T | Reddot Biotech | 48T | EUR 512 |
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Description: sandwich |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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| RD-GSK3b-Ra-96T | Reddot Biotech | 96T | EUR 731 |
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Description: sandwich |
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Rat Glycogen Synthase Kinase 3 Beta (GSK3b) ELISA Kit |
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 ELISA kit) Rat Glycogen synthase kinase-3 beta(GSK3B) ELISA kit |
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Description: Quantitativesandwich ELISA kit for measuring Rat Glycogen synthase kinase-3 beta (GSK3B) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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Rat Glycogen synthase kinase-3 beta(GSK3B) ELISA kit |
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| 1-CSB-EL009963RA | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Rat Glycogen synthase kinase-3 beta(GSK3B) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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 Rat Glycogen synthase kinase-3 beta,Gsk3b ELISA KIT |
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Rat Glycogen synthase kinase-3 beta,Gsk3b ELISA KIT |
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Rat Glycogen synthase kinase-3 beta,Gsk3b ELISA KIT |
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Rat Glycogen synthase kinase-3 beta,Gsk3b ELISA KIT |
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Rat Glycogen synthase kinase-3 beta,Gsk3b ELISA KIT |
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| JOT-EK0989Ra | Jotbody | 96 wells | Ask for price |
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Description: Rat |
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 Elisa Kit) Rat Glycogen synthase kinase-3 beta(GSK3B) Elisa Kit |
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 Rat Glycogen synthase kinase-3 beta, Gsk3b ELISA Kit |
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Rat Glycogen synthase kinase-3 beta, Gsk3b ELISA Kit |
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Rat Glycogen synthase kinase-3 beta, Gsk3b ELISA Kit |
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Rat Glycogen synthase kinase-3 beta, Gsk3b ELISA Kit |
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Rat Glycogen synthase kinase-3 beta (GSK3B) ELISA Kit |
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Rat Glycogen synthase kinase-3 beta (GSK3B) ELISA Kit |
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Rat Glycogen synthase kinase-3 beta (GSK3B) ELISA Kit |
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Rat Glycogen synthase kinase-3 beta, Gsk3b ELISA Kit |
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Rat Glycogen synthase kinase-3 beta, Gsk3b ELISA Kit |
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Rat Glycogen synthase kinase-3 beta, Gsk3b ELISA Kit |
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| MBS9304668-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Rat Glycogen synthase kinase-3 beta, Gsk3b ELISA Kit |
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Rat Glycogen synthase kinase-3 beta (GSK3B) ELISA Kit |
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 Rat Glycogen synthase kinase-3 beta,Gsk3b ELISA Kit |
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Rat Glycogen synthase kinase-3 beta,Gsk3b ELISA Kit |
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) ELISA kit for Rat GSK3b (Glycogen Synthase Kinase 3 Beta) |
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| ELK6544 | ELK Biotech | 1 plate of 96 wells | EUR 518.4 |
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Description: A sandwich ELISA kit for detection of Glycogen Synthase Kinase 3 Beta from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids. |
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 Cavy Glycogen Synthase Kinase 3 Beta ELISA Kit |
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Goat Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7245893-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 5685 |
Goat Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7245893-48StripWells | MyBiosource | 48-Strip-Wells | EUR 485 |
Goat Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7245893-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3020 |
Goat Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7245893-96StripWells | MyBiosource | 96-Strip-Wells | EUR 690 |
 Kit) ELISA kit for Rat Glycogen synthase kinase 3 beta (GSK3B) Kit |
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| KTE101131-48T | Abbkine | 48T | EUR 424.8 |
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Description: Quantitative sandwich ELISA for measuring Rat Glycogen synthase kinase 3 beta (GSK3B) Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Rat Glycogen synthase kinase 3 beta (GSK3B) Kit |
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| KTE101131-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 2702.4 |
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Description: Quantitative sandwich ELISA for measuring Rat Glycogen synthase kinase 3 beta (GSK3B) Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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ELISA kit for Rat Glycogen synthase kinase 3 beta (GSK3B) Kit |
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| KTE101131-96T | Abbkine | 96T | EUR 686.4 |
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Description: Quantitative sandwich ELISA for measuring Rat Glycogen synthase kinase 3 beta (GSK3B) Kit in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
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 Horse Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS108074-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Horse Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS108074-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Horse Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS108074-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Horse Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS108074-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
 Human Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS104711-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Human Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS104711-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Human Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS104711-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Human Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS104711-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
 Goose Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS065492-INQUIRE | MyBiosource | INQUIRE | Ask for price |
 Camel Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS094208-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Camel Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS094208-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Camel Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS094208-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Camel Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS094208-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
 Sheep Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS096386-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Sheep Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS096386-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Sheep Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS096386-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Sheep Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS096386-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
 Mouse Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS099740-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Mouse Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS099740-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Mouse Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS099740-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Mouse Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS099740-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Sheep Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7247868-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 5685 |
Sheep Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7247868-48StripWells | MyBiosource | 48-Strip-Wells | EUR 485 |
Sheep Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7247868-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3020 |
Sheep Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7247868-96StripWells | MyBiosource | 96-Strip-Wells | EUR 690 |
 Human Glycogen Synthase Kinase 3 beta ELISA Kit |
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| MBS7253535-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 5685 |
Human Glycogen Synthase Kinase 3 beta ELISA Kit |
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| MBS7253535-48StripWells | MyBiosource | 48-Strip-Wells | EUR 485 |
Human Glycogen Synthase Kinase 3 beta ELISA Kit |
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| MBS7253535-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3020 |
Human Glycogen Synthase Kinase 3 beta ELISA Kit |
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| MBS7253535-96StripWells | MyBiosource | 96-Strip-Wells | EUR 690 |
Mouse Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS728557-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 5685 |
Mouse Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS728557-48StripWells | MyBiosource | 48-Strip-Wells | EUR 485 |
Mouse Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS728557-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3020 |
Mouse Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS728557-96StripWells | MyBiosource | 96-Strip-Wells | EUR 690 |
 Canine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS082923-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Canine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS082923-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Canine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS082923-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Canine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS082923-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
 Pigeon Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS081789-INQUIRE | MyBiosource | INQUIRE | Ask for price |
 Rabbit Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS050565-INQUIRE | MyBiosource | INQUIRE | Ask for price |
 Donkey Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS047733-INQUIRE | MyBiosource | INQUIRE | Ask for price |
 Monkey Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS088155-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Monkey Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS088155-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Monkey Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS088155-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Monkey Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS088155-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
 Bovine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS091538-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Bovine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS091538-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Bovine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS091538-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Bovine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS091538-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Monkey Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7250761-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 5685 |
Monkey Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7250761-48StripWells | MyBiosource | 48-Strip-Wells | EUR 485 |
Monkey Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7250761-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3020 |
Monkey Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7250761-96StripWells | MyBiosource | 96-Strip-Wells | EUR 690 |
Bovine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7209416-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 5685 |
Bovine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7209416-48StripWells | MyBiosource | 48-Strip-Wells | EUR 485 |
Bovine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7209416-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3020 |
Bovine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7209416-96StripWells | MyBiosource | 96-Strip-Wells | EUR 690 |
Rabbit Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7242050-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 5685 |
Rabbit Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7242050-48StripWells | MyBiosource | 48-Strip-Wells | EUR 485 |
Rabbit Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7242050-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3020 |
Rabbit Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7242050-96StripWells | MyBiosource | 96-Strip-Wells | EUR 690 |
Canine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7225926-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 5685 |
Canine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7225926-48StripWells | MyBiosource | 48-Strip-Wells | EUR 485 |
Canine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7225926-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3020 |
Canine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7225926-96StripWells | MyBiosource | 96-Strip-Wells | EUR 690 |
 Human Glycogen synthase kinase-3 beta ELISA Kit |
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| EK4488 | SAB | 96 tests | EUR 497 |
 Mouse Glycogen synthase kinase-3 beta ELISA Kit |
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| EK4489 | SAB | 96 tests | EUR 579 |
Mouse Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS2887455-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 4080 |
Mouse Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS2887455-48StripWells | MyBiosource | 48-Strip-Wells | EUR 390 |
Mouse Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS2887455-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2220 |
Mouse Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS2887455-96StripWells | MyBiosource | 96-Strip-Wells | EUR 520 |
Human Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS2883314-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3290 |
Human Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS2883314-48StripWells | MyBiosource | 48-Strip-Wells | EUR 340 |
Human Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS2883314-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 1800 |
Human Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS2883314-96StripWells | MyBiosource | 96-Strip-Wells | EUR 435 |
Human Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS763250-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 3900 |
Human Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS763250-48StripWells | MyBiosource | 48-Strip-Wells | EUR 340 |
Human Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS763250-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 2045 |
Human Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS763250-96StripWells | MyBiosource | 96-Strip-Wells | EUR 455 |
Human Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS9428314-5x96Tests | MyBiosource | 5x96Tests | EUR 2420 |
Human Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS9428314-96Tests | MyBiosource | 96Tests | EUR 530 |
Mouse Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS9428315-5x96Tests | MyBiosource | 5x96Tests | EUR 2740 |
Mouse Glycogen synthase kinase-3 beta ELISA Kit |
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| MBS9428315-96Tests | MyBiosource | 96Tests | EUR 600 |
 Chicken Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS067453-INQUIRE | MyBiosource | INQUIRE | Ask for price |
 Porcine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS100323-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Porcine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS100323-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Porcine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS100323-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Porcine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS100323-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
 Hamster Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS099673-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 6725 |
Hamster Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS099673-48StripWells | MyBiosource | 48-Strip-Wells | EUR 550 |
Hamster Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS099673-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3420 |
Hamster Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS099673-96StripWells | MyBiosource | 96-Strip-Wells | EUR 765 |
Chicken Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7237191-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 5685 |
Chicken Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7237191-48StripWells | MyBiosource | 48-Strip-Wells | EUR 485 |
Chicken Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7237191-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3020 |
Chicken Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7237191-96StripWells | MyBiosource | 96-Strip-Wells | EUR 690 |
Porcine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7226342-10x96StripWells | MyBiosource | 10x96-Strip-Wells | EUR 5685 |
Porcine Glycogen Synthase Kinase 3 Beta ELISA Kit |
|||
| MBS7226342-48StripWells | MyBiosource | 48-Strip-Wells | EUR 485 |
Porcine Glycogen Synthase Kinase 3 Beta ELISA Kit |
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| MBS7226342-5x96StripWells | MyBiosource | 5x96-Strip-Wells | EUR 3020 |
The potential of concentrating on GSK3, p38 MAPK and CDKS as efficient therapeutics can be mentioned as is a short dialogue on the utilization of not too long ago developed medicine that concurrently goal two or all three of those teams of kinases. Multi-kinase inhibitors both by themselves or together with methods at present getting used corresponding to immunotherapy or secretase inhibitors for AD and knockdown for HD might characterize a simpler therapeutic strategy for these deadly neurodegenerative ailments.
