Transfection of STAT3 overexpression plasmid mediated through recombinant lentivirus promotes differentiation of bone marrow mesenchymal stem cells into neural cells in fetal rats with spina bifida aperta

Transfection of STAT3 overexpression plasmid mediated through recombinant lentivirus promotes differentiation of bone marrow mesenchymal stem cells into neural cells in fetal rats with spina bifida aperta

We investigated the affect of sign transducer and activator of transcription-3 (STAT3) on the spinal wire tissue grafts of rat fetuses with spina bifida aperta. Particularly, we hoped to establish whether or not transfection of the STAT3 overexpression plasmid will increase the survival of spinal wire transplantation with a purpose to enhance therapeutic efficacy. The…

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